Nerve Renew Reviews

Your body is filled with nerves that transmit information from all parts of your body to your spinal cord and brain. Without properly functioning nerves, you’d have trouble using all your senses and muscles. Injuries, diseases, disease treatments, aging, and lifestyle factors like diet can all negatively impact nerve function, which might result in neuralgia (nerve pain), loss of feeling in a specific body part, or impaired motor function. Approximately 7-10% of the world’s population experiences nerve pain,1 and about 30% of all nerve pain is related to diabetes.2

Nerve Renew is a dietary supplement that claims to “restore healthy nerve function and reduce discomfort or weakness.” Dietary supplements do not require approval from the U.S. Food & Drug Administration (FDA),3 so marketing statements like these might not get the kind of scrutiny they deserve. So, we investigated Nerve Renew and the research surrounding its ingredients to see if it can actually support your nerve health safely and effectively.

Nerve Renew’s vitamins, antioxidants, and herbal extracts have limited research supporting their effectiveness in improving nerve health or alleviating nerve pain in people. However, some of the B vitamins and the R-alpha lipoic acid are gaining scientific support for their roles in nerve health. When compared to other nerve health supplements, Nerve Renew is one of the safer and more reasonably priced options. While Nerve Renew may not significantly improve every customer’s nerve pain, it does contain ingredients that can support nerve health and overall wellness.

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles. To provide you with an unbiased recommendation, we extensively researched and evaluated Nerve Renew by thoroughly examining more than 50 scientific studies and articles focused on connections between its ingredients and nerve health. We also tested the customer experience and evaluated Nerve Renew against similar products to determine how it compares across the entire nerve supplement landscape.

Like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy. As more clinical research is required to substantiate nerve supplement effectiveness in humans, we’ll keep our attention on Nerve Renew, its main ingredients, and its competitors to keep this content relevant.

Nerve Renew is a dietary supplement made from 10 ingredients, all of which are naturally occurring in our bodies or the plants and meats we eat. Since dietary supplements are meant to enhance your body’s nutrients in addition to your diet, effectiveness was our top criterion. And because dietary supplements don’t require FDA approval, safety was our second most important factor. After that, we considered both cost and convenience with equal weight.

Effectiveness

Nerve Renew might be effective for some people, but research on many of its ingredients is sparse — particularly human research. Only four out of 10 ingredients have decent support that they impact nerve health or pain in some way — B1, B6, B12, and R-ALA. Most competitor nerve health supplements use some or all of these ingredients.

The National Institutes of Health points out that Vitamin D is only reliably linked to bone health.4 So, this ingredient isn’t backed by strong evidence showing that it improves nerve health. Similarly, riboflavin is not scientifically linked to nerve health, except for limited research related to its use in treating headaches and migraines.23 But even in those studies, the successful dosages were 200-400mg/day, which is significantly higher than Nerve Renew’s 8mg/day dosage. While these ingredients may provide real health benefits, there’s not enough research to support if or how they impact nerve health.

Vitamins B1, B6, and B12 are backed by more research indicating they have roles in nerve health, which is why they’re referred to as neurotropic B vitamins. Together, vitamins B1, B6, and B12 have been shown to have a synergistic relationship and improve both nerve pain and motor control.6 Vitamin B6 has been shown to help in the production of neurotransmitters, which send messages between nerve cells.7 Of these B vitamins, vitamin B12 has been the subject of the most research, so a strong connection between B12 and nerve regeneration has been established in rats and mice. More research in humans would further solidify the roles all of these B vitamins play in nerve health.

R-Alpha lipoic acid (R-ALA) is an antioxidant — a substance that may prevent or delay cell damage. Several studies on rats or people with diabetes show promise that 300-600mg/day of ALA can help reduce nerve pain and numbness and improve nerve conduction velocity (how fast signals move through nerves).8 9 10 The 600mg dose was administered intravenously in these studies, and the 300mg dose was administered orally, so Nerve Renew’s 300mg/day dose aligns with effective oral administration in studies, but studies on healthy people using ALA supplements haven’t been conducted. So, R-ALA could help people with diabetic nerve pain, but we can’t say whether it will help those with non-diabetic nerve pain.

Nerve Renew also contains an 86mg proprietary botanical blend consisting of:

• Feverfew herb extract
• Oat straw herb extract
• Passionflower herb extract
• Skullcap root extract

Most studies on these herbs have been done with rats and mice or in much higher doses ranging from 200-2500mg/day, so it’s difficult to determine what benefits they’d provide to people at this low dose.

In 2021, the National Advertising Division (NAD) of the Better Business Bureau (BBB) National Programs recommended that Nerve Renew discontinue some of its claims related to the effectiveness of its ingredients.11 Essentially, Nerve Renew was using individual studies as the basis for its claims, and the NAD didn’t feel those were enough support to make such claims (we agree). Nerve Renew did comply in this case, but the current claims on Nerve Renew’s website appear to rely on individual studies, as well, some of which do not mention the benefits Nerve Renew associates with them.

Safety

The ingredients in Nerve Renew should be well-tolerated by most individuals. The only recurring side effect in the research has been a temporarily sensitive stomach associated with vitamin B12 or R-ALA.

Nerve Renew’s daily dosage is two capsules, and most of the ingredient amounts are in line with or above Recommended Daily Allowances (RDA) or what’s been shown to be effective in studies if there isn’t an RDA. Ingredients without RDAs either aren’t considered necessary nutrients or reports of toxicity are extremely rare. We’ve listed below the daily dosages for all but the proprietary blend of herbal extracts (which we’ll touch on later).

As you can see, Nerve Renew’s daily dosage of vitamin D is above the RDA for adults but well below the daily upper limit as set by the National Institutes of Health.4 Anyone already taking a daily multivitamin or spending a significant amount of time in the sun should be wary of getting too much Vitamin D, which could lead to unpleasant symptoms like nausea and vomiting, confusion, and headache. That 25mcg dose is double the 12.5mcg dose in Nerve Regen and a lot less than the 125mcg dose in Neuroturna, which exceeds the daily upper limit.

Nerve Renew is manufactured in the U.S. When a U.S.-based company indicates it follows good manufacturing practices (GMP), it’s saying it adheres to the Federal Code of Regulations for dietary supplement manufacturing, packaging, and labeling.12 There is no official GMP seal to add to products, but Nerve Renew does include a version of one on their website, presumably to indicate their adherence.

We reached out to Customer Service to find out if Nerve Renew is GMP certified and regularly tested by third parties. We received a response within minutes, but it did not address third-party testing. The company’s website does indicate that its manufacturing facility undergoes voluntary 3rd party audits twice a year, but we had to scour the site to find this small, undetailed note. Customer Service told us that Nerve Renew is GMP certified, but we didn’t find it on the official list of GMP-certified companies.13 However, we found the same to be true for other companies claiming to be GMP certified. The lack of up-front transparency and information discrepancies don’t give us the highest level of safety reassurance we’d like to have from a dietary supplement manufacturer.

Cost

There are dozens of nerve health supplement blends available, mostly online, with prices ranging from $20-$90 for a 30-day supply with comparable ingredients and amounts. The nerve supplements with the lowest prices have fewer vitamins and herbs than Nerve Renew, and have more “other ingredients” like flavors, dyes, and preservatives.

Nerve Renew costs $69 per bottle (without subscribing) for 60 capsules, which is a 30-day supply. This is closer to the high end of the price range for all competitors but nearly identical to the price of its most direct competitor, Nerve Regen. That supplement has all the same ingredients as Nerve Renew plus one additional ingredient (acetyl-l-carnitine), and Nerve Regen costs $62 per bottle for a 30-day supply. However, Nerve Regen’s four-capsule dose is less convenient, and some of the doses of key ingredients are smaller than what you’ll find in Nerve Renew.

Nerve Renew’s price aligns more with the average for competitors if you subscribe to an automatic delivery every 30 days, where you’ll save about $20 on a 30-day supply, bringing the cost down to $49. If you buy the 3-pack of Nerve Renew, which gets you through about three months, you’ll save $60 off the purchase of three individual bottles. That’s equivalent to the subscription program savings, but the three-pack is not available on a subscription basis, so there’s no opportunity to combine the discounts.

Convenience

Nerve Renew is on the more lenient side of a dosing schedule with its two capsules per day dose. Nerve Renew’s recommendation is that you take one capsule in the morning and one at night with water, so it’s much like taking other dietary supplements. In comparison, Nerve Regen and Neuroturna require four capsules as a daily dose for a similar ingredient formulation. One bottle of Nerve Renew holds a 30-day supply, which is in line with most other nerve supplements and enough for you to start noticing potential benefits.

Nerve Renew isn’t readily available in stores or from many online retailers, so you have to buy it from either the company’s website or its Amazon store. But this aligns with most competitors as Nervive and NeuropAway are among the only oral nerve health supplement blends available in stores like CVS and Walmart. If you choose the subscription option from Nerve Renew’s website, you’ll get a new supply delivered every 30 days, which can be more convenient than running to a store for some people.

Nerve Renew is a U.S.-based company that mainly sells nerve support supplements and creams. Nerve Renew is also the name of their main dietary supplement. The company was founded by Wes Jones but is reliant on the research and advice of its Chief Medical Advisor, Dr. Don Kennedy, D.O., Ph.D., M.D., and Fellow of the American Academy of Family Physicians (FAAFP). Having only one medical advisor is common for similar companies, though PureHealth Research, maker of Nerve Regen, does have an advisory board of four doctors.

While Nerve Renew’s website seems to focus on nerve pain as a geriatric condition, nerve pain can affect anyone, and their products are suitable for most adults.

Nerve Renew combines 10 ingredients, each claimed by the company to be chosen for their scientifically-backed nerve support abilities. However, as we mentioned in our evaluation criteria earlier, all of the ingredients aren’t fully backed by science to support nerve health. That being said, Nerve Renew works similarly to other dietary supplements like multivitamins. It contains vitamins, an antioxidant, and herbal extracts that support your typical diet in providing your body with helpful nutrients.

Here’s a look at what we know one daily dose of Nerve Renew contains. We’ll explore its proprietary blend further down.

Proprietary blend

Nerve Renew’s 86mg proprietary botanical blend contains four extracts, the exact quantities of which are kept secret by the company. This is a little frustrating, but it appears to be common practice among nerve supplement manufacturers. For instance, both Nerve Regen and Neuroturna use proprietary botanical blends in their formulas.

Generally speaking, Nerve Renew is safe for most adults to take as directed. Its small ingredient list doesn’t come with any serious side effects for healthy adults, and the proprietary blend is thoroughly explained. There are established upper daily intake limits for vitamin D (100mcg), vitamin B2 (27mg), vitamin B6 (200mg), and R-ALA (2,400mg), but Nerve Renew’s amounts are well below those ceilings.

However, if you are taking other dietary supplements, you should be sure your total daily intake doesn’t exceed the upper limits for each ingredient. And despite primarily containing ingredients that are relatively common to multivitamins and similar supplements, there is always a risk of contraindication with certain medications or medical conditions. We highly recommend speaking with your doctor before taking Nerve Renew. A conversation with your doctor may be particularly important if you have diabetes, have liver disease, or are deficient in thiamine.

While Nerve Renew dietary supplement is the company’s main product, the company also sells other nerve health products, a sleep aid, and an energy supplement. As with Nerve Renew, all of these products come with company claims of scientific backing, but very limited research is presented as evidence of those claims.

Competitors like PureHealth Research (makers of Nerve Regen) have even more extensive catalogs of supplements, but these tend to spiral away from nerve support and into various other areas of health.

As a company, Nerve Renew has an A+ Better Business Bureau rating after 10 years in business.39 Most customer complaints reference difficulties with returns, the money-back guarantee, and excessive marketing emails, not Nerve Renew the product.

Nerve Renew offers free shipping on all U.S. orders over $90, and orders that don’t hit that mark will be charged $4.97 for shipping. That forces you either to sign up for a subscription or buy in bulk if you want to save on shipping. Comparatively, Neuroturna sets their free shipping threshold at $44, $1 below the cost of one bottle of their nerve support product. That ensures their customers get free shipping no matter how much they buy. If you live outside the U.S., you can still order Nerve Renew, but shipping costs vary by weight, and it could take an additional 2-4 weeks to get to you.

Nerve Renew offers a 15-30% discount depending on the product and whether you join their subscription service. Shipping is free for subscriptions.

Nerve Renew Rewards

If you decide to use Nerve Renew long-term, signing up for their rewards program can also help you save a little money. Once signed up, you’ll earn points for things like placing orders, sharing on social media, referring friends as customers, or leaving a review. Purchases earn you the least amount of points (1 per purchase), but if you create an account, leave a review, and share on social media, you’ll have enough points to earn $10 off your next purchase. The rewards can only be used to buy more Nerve Renew products.

Nerve Renew Returns

If you decide that Nerve Renew isn’t for you within 365 days of ordering, you can reach out to customer support and receive a full refund (minus the shipping cost). This is pretty standard among the competition, with Nerve Regen and Nervala also carrying 365-day policies. Only Neuroturna falls short, offering just 30 days for a return.

Nerve Renew’s return policy applies to your most recent purchase only. This is where the 1-year money-back guarantee gets confusing because even if you ordered three different products at different times, Nerve Renew will only cover the cost of your most recent purchase, not each product.

For that reason, it might be smart to get a single bottle first and then order in bulk for the next few months. That way, if you hit month four and decide it’s not for you, you can get a refund on three bottles instead of one.

Nerve Renew’s customer service is comparable to competitors' — you can call, email, or fill out a form. Nerve Renew’s customer service team got back to us within minutes of us sending an email, but they generally say they’ll respond within one business day.

The best way to get most of Nerve Renew’s ingredients into your body is through a healthy diet. But you can also find all of these ingredients on their own as dietary supplements, so if there’s only one you need or want to try instead of the full Nerve Renew blend, you can just buy that one ingredient.

Nerve Regen

Nerve Regen by PureHealth Research is the closest formulation to Nerve Renew that we found. Nerve Regen has the same 10 ingredients as Nerve Renew but in different amounts, and it adds one more ingredient — acetyl-l-carnitine (ALC). ALC is an amino acid found in your body’s cells that can help increase the activity in some nerve cells. It’s a common ingredient in nerve health supplements, but the U.S. Food and Nutrition Board (FNB) has determined ALC isn’t an essential nutrient, so there’s no RDA for it.40 Like ALA, ALC research is extremely limited.

Here’s the ingredient breakdown for a close comparison:

A 30-day supply of Nerve Regen costs about $62, while a 30-day supply of Nerve Renew costs $69 (without subscriptions). The biggest product difference besides ingredients is that you have to take four Nerve Regen capsules per day, whereas you only need to take two Nerve Renew capsules per day. If you’re not great at swallowing pills, fewer is better.

Both companies offer a 1-year money-back guarantee and are manufactured in the U.S. Both companies are Better Business Bureau (BBB) accredited, but Nerve Renew has an A+ rating while PureHealth Research has a B+ rating. Other top competitors aren’t BBB accredited. Ultimately, the fact that you get higher doses of B1, B12, ALA, and the botanical blend with Nerve Renew slightly outweighs the added ALC in Nerve Regen.

Nervala

Nervala by Barton Nutrition has fewer ingredients than Nerve Renew, so it’s really an ALA and B1 supplement. Nervala has four times as much ALA as Nerve Renew and twice as much as what was found to be effective in studies. Nervala also has only ¼ of the benfotiamine that Nerve Renew has. With Nerve Renew, you get additional vitamins and herbs. Nervala only claims to help with nerve pain, so this might explain why the company has chosen to focus on only two ingredients. In comparison, Nerve Renew claims to aid in nerve health as a whole.

Nervala is also significantly more expensive; a 30-pill bottle is only a 15-day supply because the dose for the first 60 days is two pills per day, and it costs $47. That means you’ll need to spend $94 to get a 30-day supply of Nervala as compared to Nerve Renew’s $69 for a 30-day supply. Like Nerve Renew, Nervala is manufactured in the U.S., offers a 1-year money-back guarantee, and relies on one medical doctor as its advisor. If you’re after a total nerve health supplement, Nerve Renew would be a better choice than Nervala.

Neuroturna

Neuroturna by Nuturna has 18 ingredients, 10 of which are the ones found in Nerve Renew but in different doses depending on which of Neuroturna’s three formulas you choose for comparison. In many cases, Nerve Review has the higher dose of these eight ingredients, but original Neuroturna contains a potentially dangerous 125mcg of vitamin D3. That’s 25mcg above the daily upper limit set by the National Institutes of Health.

The eight ingredients you’ll find in Neuroturna that aren’t in Nerve Renew are:

• Vitamin C
• Vitamin E
• Folic Acid
• Magnesium
• R-arginine HCL
• Acetyl-l-carnitine
• Proprietary blend (turmeric, cassia bark)

In addition to these extra ingredients, Neuroturna is available in three formulations, each with a different amount of various ingredients. Strangely, two of these three formulas hide the botanical doses in a proprietary blend, while the third lists the doses for each botanical ingredient.

While Neuroturna does include more vitamins and herbs at a lower cost, the company making it is not BBB accredited and only offers a 30-day money-back guarantee. And Neuroturna’s website mentions doctors and pharmacists assisting with formulation but doesn’t name them anywhere. For these reasons, Neuroturna doesn’t seem as trustworthy as Nerve Renew.