Cannabidiol (CBD) oil has grown into a leading health and wellness trend. It's not hard to see why: CBD has been touted to help with anxiety, pain, poor sleep, and many other health issues but lacks the intoxicating effects of THC. But with so many CBD oils on the market that all sound so similar, finding high-quality CBD oil isn't easy. The CBD industry is shrouded in scientific lingo, and it’s easy to get overwhelmed by the sheer number of products and brands.
To help you make an informed choice, we compared leading CBD brands by third-party test results, hemp quality, price, potency, and other factors. Here's a look at the best CBD oils on the market.
One of the most trustworthy names on the market, Lazarus Naturals CBD oil is high-potency and affordable.
Lazarus Naturals CBD is USDA-certified organic and undergoes extensive third-party testing. Choose between four delicious flavors, and enjoy free shipping on orders over $50.
We judge CBD products — including CBD oil — on four main criteria to help you determine which CBD oil is best for you:
Generally, we consider the quality of each oil the most important factor — it’s not worth it to take a subpar CBD oil, even when it’s inexpensive or comes with the protection of a great return policy. And since non-prescription CBD that you can get online isn’t regulated like food or prescriptions, safety (and how open a company is about its safety steps) is a close second-most important criterion to us. Costs can vary widely depending on how much CBD (and oil) you get per bottle. And customer service, while still a factor in our rankings, is of secondary importance; poor customer service won’t hurt your health (though it will probably be frustrating).
Winner: Lazarus Naturals
We primarily looked at plain CBD oils without added ingredients (other than the occasional flavoring). But even with just one main ingredient, you can still determine a CBD oil’s quality based on a few measures: its potency, what kind of CBD it is (full-spectrum, broad-spectrum, or isolate), information about the hemp the CBD came from, and certifications of the company itself. Generally, we prefer full-spectrum CBD oils because they contain cannabinoids and terpenes naturally found in hemp and require less refining, meaning there’s a smaller chance you’ll get less CBD overall. We also give preference to companies that are vertically integrated (meaning they grow and extract their own hemp rather than using a “white label” or CBD made by someone else and resold through the company) and hold a U.S. Hemp Authority certification.
Lazarus Naturals can be considered a high-quality provider of CBD because of a few main factors: it’s the only company that holds a U.S. Hemp Authority certification in addition to using USDA organic hemp to start the CBD-making process. In combination, this all but ensures that the CBD will be extremely high-quality. Likewise, the company offers standard (20mg/mL) and high-potency (50mg/mL) options for its full-spectrum CBD oil, though we prefer the high-potency oil and will focus mostly on it in this guide. Having options, though, means Lazarus Naturals gives you the widest range of personalized choices to tailor your CBD use to your needs. It’s a vertically integrated company, too, meaning that the company grows the hemp that produces your CBD, and its transparency means you know every step of the process.
Winner: NuLeaf Naturals
CBD is regulated by the FDA differently from both supplements and prescription medications. It isn’t a food item, either. And its relatively recent national legalization means there hasn’t been adequate time for too many new, formal testing strategies to form. However, there are some standard practices that we look for that the best online CBD companies use to guarantee safe products. Specifically, a CBD company should not just send its products for testing at independent laboratories to ensure that the amount of CBD and other cannabinoids in the product is accurate and check for pesticides or other potential contaminants — the company should also make these results available to the public and easy to find. It’s a red flag when a company hides these Certificates of Analysis, even if you can reach out via email to get them.
NuLeaf Naturals is the only company on our list that actively discusses its manufacturing facilities’ cGMP (current good manufacturing practices) certification from the FDA, meaning it conforms to extremely high safety requirements while the CBD is made. The company is also transparent about using CO2 extraction to get CBD and other cannabinoids from hemp; CO2 extraction is the safest way to perform this process because it’s unlikely to leave anything behind and perfectly preserves terpenes. (Ethanol extraction is also safe but is more likely to leave an unpleasant taste behind because it can also extract impurities from the hemp itself.) NuLeaf Naturals has the second-longest money-back guarantee (60 days), which gives you enough time to regularly try and see if the CBD agrees with you. Most other CBD brands only give 30 days, and while Lazarus Naturals has a 90-day return policy and U.S. Hemp Authority certification, the company uses ethanol extraction. Both brands use organic hemp at the start of their processes.
On each Certificate of Analysis, NuLeaf Naturals breaks down the cannabinoid profile, microbes, heavy metal content, pesticides, terpene profile, and any residual solvents, giving an extremely thorough run-down of what’s in every batch. Theoretically, NuLeaf Naturals will let you look at the Certificate of Analysis for both the most recent batch of each product (linked on the product page) and batch-specific results via search; at the time of writing, the link for the most recent batches was broken, which cost the company a few points. Lazarus Naturals and a few other brands also give this much depth in each Certificate of Analysis, but when combined with NuLeaf Naturals’ other safety measures and the fact that it provides a guide to help you understand what you’re reading in a Certificate of Analysis, the company goes above and beyond.
Winner: Five CBD
CBD isn’t cheap. The stronger the formula, the more expensive it tends to be at checkout, but you’ll get more out of it long-term, lowering the average cost per serving. That’s why we average prices for our best CBD oils into cost per milligram of CBD, which levels the playing field between high-price, high-potency, and bargain-price, weaker formulas when it comes to our cost ratings. We also take other ways to save into consideration, such as veterans’ discounts, subscription programs, and bulk savings options.
Lazarus Naturals doesn’t have a subscription program nor any bulk deals, but its prices are flat and relatively low for its Full Spectrum, High Potency CBD oil. Five CBD, however, offers one more size choice (3,000mg, to join 1,500mg and 6,000mg) at similar price points. More importantly, the company offers a subscription option that saves a whopping 30% off every order. This is the largest subscription savings you’ll find on our list.
For comparison, here’s a chart breaking down exactly how much you’ll pay per serving (and how much CBD you’ll get for your money):
Cost | Bottle size (mL) | Potency (mg CBD per mL) | Cost per serving (1mg) | |
---|---|---|---|---|
Lazarus Naturals | $40-$120 | 30-120mL | 50mg/mL | $0.02-$0.05 |
Five CBD | $50-$175 | 30-60mL | 50-100mg/mL | $0.03 |
CBDistillery | $35-$130 | 30mL | 17-83mg/mL | $0.05-$0.07 |
Medterra | $65-$100 | 30mL | 33-67mg/mL | $0.05-$0.07 |
Fab CBD | $39-$129 | 30mL | 10-80mg/mL | $0.05-$0.13 |
Most CBD oils will give you a full serving for less than 10 cents; $0.05 to $0.07 is average. But you can find even better — like Lazarus Naturals and Five CBD — for less than five cents per serving with up to 100mg CBD in each. Five CBD also offers significantly cheaper shipping if you don’t reach the company’s $60 free shipping threshold ($1.99 versus $5), though Lazarus Naturals offers free shipping on all orders over $50.
And while Fab CBD is the only brand on our list that offers both bulk savings and a subscription program, you’d have to spend over $300 upfront to get the best deal, which is a lot of capital many people don’t have ready to go.
Winner: Lazarus Naturals
Since CBD can be so complicated, having a knowledgeable insider who’s willing and able to help you decipher everything from potency to whether your preferred product will ship to your state is a must. Strong customer service in the CBD sphere includes the friendliness and responsiveness of the customer service team (including the number of ways you can get in touch with them). But it also includes how easy it is to purchase products, get refunds, and things like assistance programs that give discounts to groups such as veterans and those on disability. The easier a company makes it to get its product, the higher we rate its customer service score.
Lazarus Naturals has the longest return policy on our list, which is three times longer than the average policy (90 days versus 30). The company also offers a 60% discount for veterans, low-income customers, and those on long-term disability. While we’re a little disappointed that Lazarus Naturals don’t offer either a subscription program or bulk deals (which are pretty standard in the CBD world), interacting with customer service representatives was a breeze, though we had to send an email (there’s no real-time chat option on the webpage, which about half of other CBD companies have). Ultimately, because you can get such a high-potency CBD at a low cost (especially if you’re eligible for the assistance program), Lazarus Naturals offers the most convenient CBD oil.
CBD’s only been federally legal in the U.S. since 2018, meaning there have only been a few years where it’s been possible for us all to become acquainted with the substance — and for online retailers to build national notoriety.
We’ve spent hundreds of hours researching and testing various CBD products, from full-spectrum oils to isolate gummies with herbal additions. Over the course of our studies, we’ve read over 75 clinical studies examining how CBD works in the body and what it can (and can’t) actually do to improve your health, separating CBD oil from snake oil. For this review, we tried CBD oils from Lazarus Naturals, CBDistillery, and Medterra, among other brands and specific products, to give you the most realistic idea of how CBD oil might work for you.
Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles. Like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy. To keep things up to date, we will monitor the CBD landscape and update this page as information changes.
Thanks to complicated price structures based on shifting doses, potencies, and volumes, as well as different kinds of CBD and certifications that all sound the same, it can be hard to tell if you’ve found the best kind of CBD oil for you. We’ve put together this chart to lay out all of the most important information at the outset.
Because we often recommend individual products from some companies and a broader range from others, we’ve also made a chart breaking down some company-wide facts for each of the companies that make our top eight CBD oils.
Cannabidiol (CBD) is one of over 140 naturally occurring phytocannabinoids, the main active compounds in cannabis.1 Unlike THC, the cannabinoid most people are familiar with, CBD can't get you high. It's usually extracted from hemp, a variety of cannabis with a low THC concentration (below 0.3%).
CBD oil is the most popular CBD product but is far from the only one. Other options include:
CBD oil, specifically, is hemp extract dissolved in a carrier oil (like MCT oil, coconut oil, or sunflower seed oil). Since CBD is hydrophilic and binds to oils rather than water, the carrier oil helps your body absorb CBD. CBD oil is best taken sublingually: when you place a few drops of CBD oil under your tongue, some is absorbed directly into the blood vessels that are close to the surface in the thin tissue under your tongue. This bypasses the digestive tract, greatly improving CBD's absorption.
There are four main ways to administer CBD, each with its strengths and weaknesses:2
Each of these different methods has its own benefits and works better in some situations than others. For example, if you’re experiencing high levels of anxiety and need help calming down quickly, an inhaled form of CBD (which takes effect within a few minutes and can promote longer, slower breathing patterns, which also helps to lower anxiety levels) may be a better option than oral CBD, which may take up to two hours to kick in. Here are the major differences between each method of CBD ingestion:
Absorption | Time to Feel Effects | Average Duration | Products | |
---|---|---|---|---|
Sublingual | Medium | 15-40 min | 4-6 hours | Oil, spray, isolate |
Oral | Low | 30-120 min | 4-8 hours | Capsules, edibles, beverages, isolate |
Inhalation | Medium-high | Within 1 min | 1-4 hours | Vape oil, hemp flower |
Topical | Medium* | 10-60 min | 2+ hours | Cream, body oil, patch |
*Topical CBD is absorbed reasonably well, but scientists still aren’t sure if it makes its way into the bloodstream for systemic circulation.
CBD is one of several cannabinoids found in the cannabis plant, alongside the well-known cannabinoid THC (which causes the psychoactive “high” associated with cannabis). There are other minor cannabinoids, such as CBN, CBG, and CBA, that you may see alongside CBD in oils and other supplements. Our bodies are full of two kinds of cannabinoid receptors, called CB1 and CB2 receptors. CB1 receptors are mostly found in the brain and control the psychoactive effects of cannabinoids, and CB2 receptors are found throughout the body and have more anti-inflammatory and immunosuppressive qualities.4
Unlike most cannabinoids, CBD doesn't interact directly with your cannabinoid receptors. But it can increase levels of anandamide, one of the two main endocannabinoids produced by our bodies.5 Endocannabinoids are the main players in the human body's endocannabinoid system (ECS). Discovered in the 1990s, this system regulates virtually every major process — including immune function, pain, metabolism, digestion, and brain function — to maintain homeostasis.6
Most standard drugs have one or several mechanisms of action (how they produce their effects). CBD appears to have dozens of mechanisms of action, affecting many receptors and systems in the body.7 One recent study found that it affects 76 distinct molecules, including various receptors, neurotransmitter systems, transporter proteins, and enzymes. This may explain why CBD appears to have so many beneficial properties.
Some of these beneficial properties include:8
Most of the reported evidence has been limited to animal studies, so more clinical trials are needed to confirm these effects in humans. So far, the clinical data is strongest for CBD's anti-seizure effects in rare types of treatment-resistant epilepsy.9 The FDA approved CBD as a medication for two types of seizure disorders (Lennox-Gastaut and Dravet syndromes) in 2018.
There's no one-size-fits-all recommendation for CBD. Your height and weight, genetics, anxiety levels, sleep history, pain tolerance, and even what you’ve had to eat that day (among other things) affect how your body absorbs and reacts to CBD. Different brands and products will also work distinctively, as varying doses, terpene profiles, and extraction methods shift CBD’s chemical composition. That's why the best approach is to “start low and go slow,” gradually working your way up to the dose that provides you with relief.10
Insider Tip: Some CBD brands say they’re USDA organic. This is a little misleading — the USDA won’t label CBD itself as organic, but it will award organic status to the hemp the CBD came from.
CBD oils contain one of three types of CBD:11
Let’s take a look at how they differ so that you can choose the best one for your needs.
Full-spectrum CBD is a whole-plant hemp extract containing all of the cannabinoids (including CBN, CBC, CBG, and less than 0.3% THC), terpenes (aromatic compounds), flavonoids, and other natural compounds found in the plant. These molecules support CBD, creating what some refer to as the entourage effect, where components work together synergistically for greater therapeutic benefits.12 Since full-spectrum CBD retains all of these additional compounds, it seems to have the most functional effects. For example, one study in epilepsy patients found that CBD-rich cannabis extract was up to four times more effective than pure CBD.13 We generally recommend full-spectrum CBD extract unless you need to completely avoid THC (whether you’re particularly sensitive to the effects or if you need to pass a drug test).
Broad-spectrum CBD is very similar to full-spectrum CBD, but with one small difference: the low levels of THC have been scrubbed clean. Since it retains the other cannabinoids, terpenes, and flavonoids, it still provides nearly the same effectiveness as full-spectrum CBD. If you can’t ingest any THC for drug tests, are sensitive to THC, or live in a state where any amount of THC in CBD is illegal, broad-spectrum is going to be your best option. However, keep in mind that broad-spectrum products can still contain undetectable, trace amounts of THC. Although unlikely, it's theoretically possible to ingest enough THC to test positive on a drug test if you regularly use a broad-spectrum CBD product.
Isolate is pure CBD with no other compounds. Because of this lack of extra oomph, it won’t have the added benefits of full- and broad-spectrum CBD, but it is generally cheaper. So while it’s not the best option, if you’re on a budget and can’t (or don’t want to) ingest THC, CBD isolate may still be a reasonable option for you. Our testers found it took about 10mg more, per dose, of CBD isolate to see roughly the same effects as full-spectrum CBD.
Researchers have concluded that CBD is a relatively safe, non-intoxicating, and non-addictive substance.14 According to a 2018 report by the World Health Organization (WHO), CBD is generally well-tolerated with a good safety profile.15 Safety studies also report that CBD has mostly minor side effects and that people tolerate daily doses as high as 1,500mg (1.5g).16 However, like anything you take, there are some possible side effects. These include:
The good news is that all these side effects are usually mild. More importantly, they've only been reported by studies using continuous high oral doses of purified CBD isolate, which is far from how most individuals use CBD. (Taking full-spectrum CBD sublingually is much more common than just swallowing pure isolate.) And if you’re taking CBD to help you sleep, you’re actually using these side effects for your benefit. But if you have low blood pressure, take blood pressure medications, or know you have a particularly sensitive stomach, talk to your doctor before trying CBD to ensure it’ll be right for you.
Some CBD brands will warn you not to take CBD if you take any medications that recommend you not consume grapefruit. This is because those medications are broken down by certain liver enzymes, called cytochrome P450 enzymes, and consuming CBD (or grapefruit) will stop them from working.17
If you take any of these medications, it isn’t a good idea to try CBD:
Cytochrome P450 enzymes metabolize almost half of all drugs, so this is a non-exhaustive list. This list from Indiana University’s School of Medicine has a relatively comprehensive table of drug interactions, but most medications that are contraindicated will have a notice on the bottle. If you have questions about whether or not taking CBD will affect any of your prescriptions, check with your doctor or pharmacy first.
Just about any healthy adult who isn’t taking a medication broken down by a cytochrome P450 enzyme could find benefits from trying CBD oil. It’s particularly useful for people who can’t swallow pills, as the oil is easy to take sublingually (or if you’re like some of our testers, mixed into teas or cooked into foods — just be sure you cook it at relatively low temperatures so it doesn’t break down). And since very potent CBD oils are available, it’s a better option than something like a gummy or capsule for people with high tolerances or who need to take a substantial amount of it to see relief.
Although more clinical research is needed for most conditions, there's evidence that CBD can help people with the following concerns:
There’s also some evidence that CBD can be a helping hand for people struggling with addiction, particularly opioid addiction. Since blocking cannabinoid receptors (particularly CB1) seems to limit how rewarding opioids are in the brain, there are some theories (including data from leading neuroscientist Dr. Yasmin Hurd from the Mount Sinai Medical Center) that CBD might be able to fight the opioid epidemic. CBD has been shown to reduce opioid cravings and opioid painkiller use, alongside other anti-addictive effects.24 25 26
Trying CBD won’t cure substance abuse disorder, though. If you’re struggling with addiction and ready to take the next steps toward recovery, reach out to the Substance Abuse and Mental Health Services Administration (SAMHSA)’s National Helpline at 1-800-662-HELP (4357).
Editor's choice and best budget option
Our top pick goes to the Full-Spectrum, High-Potency CBD oil tincture from Lazarus Naturals. Lazarus Naturals is an employee-owned and vertically integrated company, meaning that it controls every step, from growing the hemp to manufacturing the end products.
This tincture is strong at 50mg/mL and comes in two bottle sizes — 30 and 120mL — and three flavors (classic, chocolate mint, and strawberry lemonade). This is a pretty big difference from our last review, where two other bottle sizes (one smaller and one between 30mL and 120mL) and one other flavor (French vanilla mocha) were offered. Strawberry lemonade is a new flavor addition in the last year.
Our testers tried the classic (unflavored) version of this CBD oil. Immediately, they noted that it had a complex flavor: earthy, somewhat bitter, and somewhat fruity, like high-percentage dark chocolate. A close look at Lazarus Naturals’ Certificate of Analysis for this product confirms that its top terpene (34.8% of the total terpene count, in the case of our batch) is farnesene, an earthy, bitter terpene most often found in green apple skins.
On the Certificate of Analysis (which is easy to access from every product page), you’ll find Lazarus Naturals’ third-party tests for potency, pesticides, and heavy metals, as well as a breakdown of residual solvents from the extraction process and cannabinoid content. This is one of the longest and most comprehensive Certificates of Analysis we’ve seen. Lazarus Naturals uses an ethanol alcohol extraction, which isn’t our favorite but still results in a high-quality CBD oil.
Overall, our testers were pleased with this CBD oil. It was easy to draw up and measure with obvious lines on the dropper, though it’s a dark liquid, so you’ll have to keep an eye on it as you draw up. They experienced a strong sense of relaxation and calmness that came on within half an hour and lasted about four hours, and while it didn’t necessarily make them more sleepy, it did relieve a little bit of stiffness and soreness after sitting at a desk all day.
Insider Tip: Be sure your order is right when you’re on the initial checkout page — there’s no additional step to review your order after inputting your billing information.
This CBD oil might look like it costs a lot, but ultimately you’ll only pay two or three cents per milligram of CBD. (The average price of CBD oil is about nine cents per milligram.) A 30mL bottle costs $40, and a 120mL bottle costs $120. If you order at least $25, you can split your order cost into four equal payments without interest through a partnership with Sezzle, too.
On top of that, Lazarus provides free shipping on orders over $50; you’ll pay $5 if you order a 30mL bottle. The company also offers a 90-day return policy, the most generous in the CBD sphere (30 days is standard), and a 60% discount for veterans, low-income families, and individuals with disabilities.
Strongest THC-driven entourage effect
If you're looking for a full-spectrum CBD oil with a more pronounced THC presence, we recommend Five CBD's CBD+THC Oil. Notice how we include that as both a positive and a negative in the breakdown above; it's because this polarizes people. Like all Five CBD products, it provides higher-than-average amounts of minor hemp cannabinoids. With most full-spectrum oils, you'll find a 10:1 or lower ratio of CBD to minor hemp cannabinoids, but Five CBD's tincture has a ratio of 5:1. Equally noteworthy, however, is that it contains a relatively whopping 2mg THC per serving. This amount is very minor compared to recreational marijuana servings in states where that is legal, but it is significantly higher than many other full-spectrum CBD products. At that level, depending on your sensitivity to THC, you could experience a more effective medicinal treatment along with a minor brain fog or buzz (something akin to what people experienc with some antihistamines or cold medications, for instance). Or you could experience a slightly more psychoactive buzz from this CBD. It's a potent and effective option if you know your body reacts well to a small amount of THC with your CBD, but it isn’t a good option for people who are sensitive to THC, are regularly drug tested, or just don’t want to consume THC at all.
This CBD comes in three different size and potency combinations: you can get a 30mL bottle of 50mg per mL CBD (1,500mg total), a 30mL bottle of 100mg per mL CBD (3,000mg total), or a 60mL bottle of 100mg per mL CBD (6,000mg total). You can get it in both citrus and mint chocolate flavors, and reviewers generally report that both flavors are accurate (and that the CBD oil works better when you take it without food). However, it is slightly sweetened with stevia, which can be rough on some sensitive stomachs.
Five CBD uses U.S.-grown hemp to make its CBD and provides Certificates of Analysis for the latest batch on each product page. These analyses are comprehensive, breaking down purity, potency, heavy metals, pesticides, and other contaminants, though it doesn’t go as far as Lazarus Naturals in specifying terpenes or breaking down the minor cannabinoid content.
The company offers some of the lowest prices per milligram of CBD ($0.03) uniformly across all sizes and potencies. You can also get a 30% discount on all orders through the Subscribe and Save option, which gives you free shipping (otherwise unlocked when you’ve spent $60 or more) and a new bottle of CBD once a month. Here’s a quick breakdown of how much you’ll spend on a bottle of full-spectrum CBD oil from Five CBD:
Cost (one-time) | Cost (subscription) | |
---|---|---|
1,500mg | $49.99 | $34.99 |
3,000mg | $89.99 | $63 |
6,000mg | $174.99 | $122 |
If you don’t meet that $60 one-time order minimum free-shipping requirement, expect to pay a mere $1.99. This is the lowest shipping cost on our list, and combined with a reasonable 30-day return policy (not the best, but still average) and a deep discount for veterans, students, healthcare workers, and first responders, Five CBD offers a fantastic deal for people who don’t mind the mind-altering effects of THC when they take CBD.
Best high-potency option
CBDistillery offers a huge, often unwieldy marketplace of CBD oils, gummies, capsules, and more. Every product is listed separately, even when it’s different versions of the same product. Ultimately, we think the company’s 5,000mg tincture is your best option for an ultra-high potency CBD oil.
As a full-spectrum product with 167mg of CBD per mL (one full dropper), this is one of the strongest CBD oils you'll find. Most high-potency offerings from other brands contain only 50-83mg of CBD per mL. When our testing team tried a different version of CBDistillery’s CBD oil (CBN + CBD Sleep Tincture), they noted that the oil didn’t have much of a taste at all, which is nice for people who struggle with the often bitter, earthy taste that comes with unflavored CBD. There’s currently one flavored equivalent offered year-round — mango — but CBDistillery occasionally offers seasonal flavors like peppermint in the winter.
This tincture is certified by the U.S. Hemp Authority, highlighting CBDistillery's commitment to stringent hemp industry quality standards, but it’s one of the only CBDistillery products that is certified. Know that you might not get a product as high-quality if you opt for something else from the company.
This CBD costs $0.05 per milligram, which is less expensive than average, but remember that there is 5,000mg in this bottle. A one-time purchase will cost $240, or $168 (a 30% savings with free shipping) if you join CBDistillery’s subscription program. The subscription is generally worth it for the free shipping alone; though this CBD oil meets the $75 threshold for free shipping, it’d cost $9 if you opt for a less-expensive, lower-potency bottle. And you might need to — at the time of writing, this particular strength is out of stock. While CBDistillery products come back into stock relatively quickly, you might need to purchase a lower dose 2,500mg tincture bottle in the meantime.
CBDistillery is also one of two companies on our list that doesn’t offer savings programs for disadvantaged customers or veterans.
Best THC-free option
Like Five CBD’s tincture, Medterra’s Ultra Broad Spectrum CBD Oil has a high concentration of minor cannabinoids (like CBG, CBC, CBN, and terpenes), which contribute to CBD oil’s main benefits. This tincture has an elevated 10:1 ratio of CBD to minor cannabinoids, whereas most broad-spectrum CBD oils have a ratio of 20:1 or lower. It’s average compared to full-spectrum CBD oils, but it’s going to be your best option if you have to stay away from THC completely.
Medterra's CBD oil is available in medium (33mg/mL) and high (67mg/mL) potencies, with 1,000 and 2,000mg of CBD per bottle, respectively. Both sizes come in unflavored, citrus, and strawberry mint flavors. Recently, Medterra replaced a chocolate mint flavor with strawberry mint, which customers think compliments the oil nicely. All Medterra products are U.S. Hemp Authority certified and made in America, and a link to the Certificate of Analysis for the most recent batch of CBD oil is available directly on the product page. This certificate is relatively comprehensive, breaking down cannabinoid content (but not terpenes), pesticides, residual solvents, microbial contaminants, and heavy metal contents.
This CBD oil costs about $0.05-0.06 per mL, which is about average. However, the company also offers a 30% savings with free shipping through a subscription program, where you can choose how often you want a new bottle delivered (every one or two months). Here’s how much the subscription program will save you:
Cost (one-time) | Cost (subscription) | |
---|---|---|
1,000mg | $64.99 | $45.49 |
2,000mg | $99.99 | $70 |
Medterra offers free shipping for all subscription orders and costs $4.99 for orders less than $75. The company also offers a discount program for students, military members (active and veteran), and people on long-term disability, though it’s unclear how much you’ll save without verifying your status. And, like most companies on our list, Medterra offers a 30-day return policy. Ultimately, the savings are good, but don’t opt for Medterra for the price alone — it’s nothing special.
Best flavored CBD oil
Taking CBD oil correctly means letting it sit under your tongue for 30 seconds to a minute before swallowing it. That means you’re forced to sit with the flavor for at least that long, and full-spectrum CBD oil has a distinct taste to it (which varies slightly depending on the terpene profile). If you're not a fan of the taste of full-spectrum oil, Fab CBD has you covered with five distinct flavors. Aside from the standard natural flavor, you can also choose from citrus, mint, vanilla, or berry.
These 30mL CBD oils are available in four strengths:
California's Fab CBD uses organic Colorado hemp to make its products and provides detailed third-party lab test reports. It also donates to worthy causes like Operation Underground Railroad and the Make-A-Wish Foundation. While it’s on the higher side of our price range, we like having a CBD option that tastes good. Combined with the easy-to-see, well-labeled dropper, and particularly low potency options, this is a great option for beginners who are curious about CBD but aren’t ready to commit to the heavy-hitters yet and those who are casual CBD users.
Fab CBD uses ProVerde Laboratories as its third-party testing organization, which is a common and well-regarded pick. The company even goes as far as to link to ProVerde’s website on its lab reports page, which is available in the footer of every page. The Certificates of Analysis are short (a four-page breakdown with a leaf-print background) but include terpenes, cannabinoid content, pesticides, and heavy metals.
You can purchase this CBD oil in packs of one or three bottles, and both single and three-packs are eligible for 20% savings through Fab CBD’s subscription program. Here’s a quick look at exactly how much you’ll pay:
One-time, single | Subscription, single | One-time, 3-pack | Subscription, 3-pack | |
---|---|---|---|---|
300mg | $39 | $31.20 | $111 | $89 |
600mg | $59 | $47 | $171 | $137 |
1,200mg | $99 | $79 | $291 | $232.80 |
2,400mg | $129 | $103 | $381 | $304.80 |
You’ll earn free shipping on orders over $99, making this the hardest threshold on our list. However, if you order any three-pack or a one-time order of the two higher dosages, you’ll meet this limit, so it’s not unreachable. Just know you’ll have to pay a little more out of pocket for a small bottle. Fab CBD has a reasonable return policy and a 30-day money-back guarantee, but it doesn’t stand out for any financial benefits.
NuLeaf Naturals CBD Oil is a full-spectrum option we think is a good alternative for people who want to try full-spectrum CBD but aren’t sure if they enjoy high-potency, unflavored CBD. You can get this oil in a wide range of sizes:
No matter what size you get, all formulas have 30mg CBD per 1mL serving. It costs 7-10 cents per mg of CBD, depending on the volume, which is about average. NuLeaf Naturals does offer 20% savings with its subscription program, shipping a new bottle to you every 2, 4, 6, 8, or 12 weeks.
Here’s a quick look at how much you’ll pay for each bottle:
Cost (one-time) | Cost (subscription) | |
---|---|---|
300mg | $19 | $15.20 |
900mg | $49 | $39 |
1,800mg | $89 | $71 |
3,000mg | $139 | $111 |
6,000mg | $249 | $199.20 |
If you’re looking for a small order of CBD and don’t mind the way full-spectrum CBD tastes, this is an even better option for beginners than Fab CBD’s 300mg option because the equivalent size is less than half the price. There’s a slightly lower free shipping threshold — you need to order at least $74 worth of CBD to unlock it — and the company’s money-back guarantee is twice as long at 60 days, making it the second longest on our list. It’s also one of the only companies on our list that uses a cGMP-certified facility in production, which is a huge plus.
Endoca offers two formulas: regular and raw. Raw is an unprocessed tincture with high levels of CBDa (cannabidiolic acid), CBD's “parent cannabinoid.” CBDa is what’s naturally found in the hemp plant and turns into CBD during extraction. Research on CBDa is still fledgling, so we don’t know as much about it as CBD, but we do know that it works differently than CBD. Rather than binding to cannabinoid receptors, it seems to work as a COX-2 inhibitor, which means it appears to stave off inflammation and pain better than plain CBD and has strong anti-emetic properties.29 30 While CBD is not a cure or treatment, people undergoing chemotherapy and struggling with intense nausea and vomiting may find more success with Endoca’s Raw CBD oil than other kinds of CBD oil.
Much like NuLeaf Naturals, Endoca uses CO2 extraction methods on its organic hemp to make its CBD oil. All of these oils are completely vegan and GMO-free, which is standard, but also include a few other handy nutrients:
These additional fatty acids work well in oil and provide additional benefits above and beyond CBD.
Notably, it’s difficult to get to the Certificates of Analysis for Endoca’s products. (It’s the last link under the “Support” tab, labeled as “CBD Quality report.”) All of the information is bundled by batch, so you’ll need to know a batch number to get specific information, but you can also click through and read more if you want to verify consistency. These Certificates of Analysis aren’t as sleek as other companies and can be a bit difficult to read at times, but they include all of the important information we expect. It appears that all of the testing reported on these certificates is done in-house, which is not common. According to the website, the company uses both in-house and third-party testing, but it’s not obvious where these third parties come in.
You can get this CBD oil in medium, strong, and (if you live in the U.S.) extra strong versions and multiple bottle sizes. Likewise, you can also get medium and strong CBD oils unflavored or with chocolate mint flavoring. Endoca’s CBD oil — especially the raw formula — has a particularly strong hemp taste, so it can be a little pungent for people who aren’t used to it or just don’t like hemp’s earthy flavor. However, note that the flavored options are about $10 less expensive than their unflavored equivalents across the board, and the company doesn’t offer its raw formula with flavoring options at this time.
Right now, Raw Strong is the only formula you can get in a small 2mL bottle; all other formulas come in 10mL and 30mL bottles. Endoca also doesn’t have any subscription or bulk savings options, which we found to be a bit of a bummer, but isn’t unheard of in the CBD world.
Here’s how much you can expect to pay for each of Endoca’s CBD oils:
2mL bottle | 10mL bottle | 30mL bottle | |
---|---|---|---|
Medium, 300mg | $31 | $83 | |
Raw Medium, 300mg | $31 | $83 | |
Medium, chocolate mint, 300mg | $22 | $59 | |
Raw Strong, 1,500mg | $26 | $92 | $246 |
Strong, 1,500mg | $129 | $348 | |
Strong, chocolate mint, 1,500mg | $69 | $186 | |
Raw extra strong, 3,000mg* | $199 |
*At the time of writing, the extra-strength CBD oil is out of stock.
You can also get free shipping on orders over $74, and there’s a 30-day return policy in case you decide CBD isn’t right for you. If you’re a veteran, from a low-income household, or someone with a long-term disability, you’ll also qualify for Endoca’s support program.
Colorado's R+R Medicinals is not the biggest brand out there, but its certifications, reviews, and high-quality products speak for themselves. This veteran- and employee-owned company uses USDA-certified organic hemp to create its CBD and, as we expect out of all CBD brands, provides detailed third-party lab reports. These lab reports are incredibly comprehensive, rivaling NuLeaf Naturals and Lazarus Naturals in terms of the quantity of information. They include potency (with each cannabinoid broken down per mL and per bottle), terpenes, microbial contaminants, residual solvents, pesticides, and heavy metal content, as well as quick summaries for those who don’t want to read through all nine pages of the packet.
We especially appreciate the company’s in-depth Supplement Facts information, which is one of the only ones we’ve seen that breaks down not only how much CBD is present but also other cannabinoids and THC per milligram in each dose. While we don’t have an exact number for most of R+R Medicinals’ competitors, Five CBD has 2mg THC per serving, and all other companies fall below 0.3% THC (with some even advertising 0.2% or less) in full-spectrum oils. If a slightly higher THC content concerns you, we recommend sticking with the company’s broad-spectrum THC-free formula.
R+R Medicinals CBD Oil stands out for being one of the only tinctures on the market that's both certified by the U.S. Hemp Authority and comes from USDA-certified organic hemp, alongside Lazarus Naturals. You can choose from a full- or broad-spectrum formula; both are available in a fresh mint flavor, but you can only get the full-spectrum oil unflavored if mint isn’t your thing. Likewise, you can get the full-spectrum oil in 500, 1,000, and 2,500mg potencies, but the broad-spectrum oil is only available in 1,000mg bottles.
Here’s a quick breakdown of your options for all three of these CBD oils:
THC-free Fresh Mint | Fresh Mint | Unflavored | |
---|---|---|---|
CBD type | Broad-spectrum | Full-spectrum | Full-spectrum |
Cost range | $55-$150 | $35-$275 | $35-$275 |
Size | 1oz | 1oz | 1oz |
Potency | 1,000mg | 500mg, 1,000mg, 2,500mg | 500mg, 1,000mg, 2,500mg |
CBD per serving | 33.3mg | 16.7mg, 33.3mg, 41.6mg | 16.7mg, 33.3mg, 41.6mg |
Packs? | 1, 3 | 1, 3 | 1, 3 |
R+R offers free shipping on orders over $60 and all subscriptions, as well as a 25% veteran discount. The company’s 60-day return policy is generous and twice as long as the average, but it doesn’t top Lazarus Naturals’ 90-day guarantee. Above all, if you like knowing what’s in your CBD, don’t mind regularly re-ordering (which is why the subscription program is a great idea here), or enjoy a more earthy taste to your CBD, R+R Medicinals may be a good option for you.
CBD oil isn’t going to be the best fit for everyone. It’s expensive, especially if you need a large dose, and you may find that it takes too long to kick in. Or maybe CBD isn’t right for you in general, and you find it makes you sleepy but doesn’t quiet your anxiety. Here are a few other options you might find work better for you based on the three most common reasons people try CBD:
While generalized anxiety disorder, social anxiety, and PTSD all have promising studies backing up CBD’s use as a method of care, there is little research looking at other anxiety disorders and things previously classified as anxiety, such as panic disorder and obsessive-compulsive disorder (OCD). Generally, botanicals and supplements that target serotonin uptake, much like prescription antidepressants (like SSRIs), are your best option.27 Saffron and ashwagandha have the most clinical research backing up their influence on serotonin and anxiety levels (with ashwagandha being notably strong), but GABA supplements can also decrease your anxiety levels and promote a sense of calm, as can L-theanine. Taking a supplement on its own will likely be less expensive than CBD, but high-potency doses or bottles that contain more than 30 days’ worth of servings may cost slightly more. You might also find that you need to add one of these ingredients to your CBD to experience the most anxiolytic (anti-anxiety) effects. Luckily, we’ve rounded up the best CBD options for anxiety, so check those out first before throwing in the towel.
Always get checked out by a doctor first if you’re experiencing chronic pain; there may be an underlying condition that can be addressed more thoroughly by traditional pharmaceuticals. However, doctors aren’t always the best at catching and managing chronic pain. Anti-inflammatory supplements are surprisingly common, with a few standout products we’d recommend most. Curcumin (turmeric) is particularly apt at decreasing inflammation, and several kinds of CBD products include curcumin for this reason. Likewise, omega-3s have excellent anti-inflammatory properties (and many Americans don’t get enough of them); these are easiest to find as fish and krill oils, but they’re going to be more difficult to find and more expensive if you’re a vegan or vegetarian.28
Melatonin and valerian root should be your go-to next steps for sleep aid. There’s also some evidence that magnesium can improve your sleep habits, as well as ashwagandha, chamomile, and passionflower, but start with melatonin and valerian root. Melatonin is extremely common and easy to find in high-quality supplements in your local pharmacy, but it’s better for people who need help getting to sleep. If you have a hard time staying asleep, try valerian — there’s some evidence it might help you fall asleep faster and stay in a deep sleep for longer. There are also some heavier-duty sleep aids you can get from your doctor as a prescription, such as trazodone and Ambien. Or, try minimizing your blue light exposure in the hours before bed and keep your phone in another room — blue light can disrupt natural melatonin production, throwing off your sleep rhythm.
Other forms of CBD may be a better fit, depending on why you want to use CBD. The time it takes for CBD to start working may affect your overall experience, as can the length of time it stays active. If you are particularly sensitive to high doses of CBD or have difficulty measuring the same amount in a dropper every time, something like topical CBD (for pain, soreness, or fatigue) or a gummy or capsule (for a slower onset time but longer-lasting effects, which is particularly useful for sleep) may work better for you. Struggling to get a good night’s sleep might also mean looking at CBD and CBN — our testers found that using a combined CBD and CBN oil improved their quality of sleep, though it didn’t make falling asleep happen any faster. (You can learn more about the best kinds of CBD to help you sleep in our guide, too.)
Sources
Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Sampson P. B. (2021). Phytocannabinoid pharmacology: medicinal properties of Cannabis sativa constituents aside from the "big two". Journal of Natural Products, 84(1), 142–160.
Borodovsky, J. T., Crosier, B. S., Lee, D. C., Sargent, J. D., & Budney, A. J. (2016). Smoking, vaping, eating: Is legalization impacting the way people use cannabis? The International Journal on Drug Policy, 36, 141.
Millar, S. A., Stone, N. L., & Yates, A. S. (2017). A systematic review on the pharmacokinetics of cannabidiol in humans. Frontiers in Pharmacology, 9.
Howlett, A. C., & Abood, M. E. (2016). CB1 & CB2 receptor pharmacology. Advances in Pharmacology (San Diego, Calif.), 80, 169.
Deutsch, D. G. (2015). A personal retrospective: Elevating anandamide (AEA) by targeting fatty acid amide hydrolase (FAAH) and the fatty acid binding proteins (FABPs). Frontiers in Pharmacology, 7.
Skaper, S. D., & Marzo, V. D. (2012). Endocannabinoids in nervous system health and disease: The big picture in a nutshell. Philosophical Transactions of the Royal Society B: Biological Sciences, 367(1607), 3193-3200.
Most, J., Bryk, M., & Starowicz, K. (2020). Cannabidiol for pain treatment: Focus on pharmacology and mechanism of action. International Journal of Molecular Science, 21(22), 8870.
VanDolah, H. J., Bauer, B. A., & Mauck, K. F. (2019). Clinicians' guide to cannabidiol and hemp oils. Mayo Clinic proceedings, 94(9), 1840–1851.
Golub, V., & Reddy, D. S. (2021). Cannabidiol therapy for refractory epilepsy and seizure disorders. Advances in Experimental Medicine and Biology, 1264, 93–110.
Lucas, C. J., Galettis, P., & Schneider, J. (2018). The pharmacokinetics and the pharmacodynamics of cannabinoids. British Journal of Clinical Pharmacology, 84(11), 2477–2482.
Cather, J. C., & Cather, J. C. (2020). Cannabidiol primer for healthcare professionals. Proceedings (Baylor University. Medical Center), 33(3), 376-379.
Russo, E. B. (2017). The case for the entourage effect and conventional breeding of clinical cannabis: No “strain,” no gain. Frontiers in Plant Science, 9.
Pamplona, F. A., & Coan, A. C. (2017). Corrigendum: Potential clinical benefits of CBD-rich cannabis extracts over purified CBD in treatment-resistant epilepsy: Observational data meta-analysis. Frontiers in Neurology, 9.
Larsen, C., & Shahinas, J. (2020). Dosage, efficacy and safety of cannabidiol administration in adults: A systematic review of human trials. Journal of Clinical Medicine Research, 12(3), 129-141.
Expert Committee on Drug Dependence. (2018, June). Cannabidiol (CBD) Critical Review Report. World Health Organization.
Bergamaschi, M. M., Queiroz, R. H., Zuardi, A. W., & Crippa, J. A. (2011). Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current Drug Safety, 6(4), 237–249.
Balachandran, P., Elsohly, M., & Hill, K. P. (2021). Cannabidiol interactions with medications, illicit Substances, and alcohol: A comprehensive review. Journal of General Internal Medicine, 36, 2074-2084.
Skelley, J. W., Deas, C. M., Curren, Z., & Ennis, J. (2020). Use of cannabidiol in anxiety and anxiety-related disorders. Journal of the American Pharmacists Association, 60(1), 253-261.
Babson, K. A., Sottile, J., & Morabito, D. (2017). Cannabis, cannabinoids, and sleep: A review of the literature. Current Psychiatry Reports, 19, 23.
Boyaji, S., Merkow, J., Elman, R. N. M., Kaye, A. D., Young, R. J., & Urman, R. D. (2020). The role of cannabidiol (CBD) in chronic pain management: An assessment of current evidence. Current Pain and Headache Reports, 24, 4.
Frame, N., Stapleton, E., Iturriaga, C., Ganz, M., Rasquinha, V., & Duarte, R. (2022). Cannabidiol as a treatment for arthritis and joint pain: an exploratory cross-sectional study. Journal of Cannabis Research, 4, 47.
García-Gutiérrez, M. S., Navarrete, F., Gasparyan, A., Ostrich-Olivares, A., Sala, F., & Manzanares, J. (2020). Cannabidiol: A potential new alternative for the treatment of anxiety, depression, and psychotic disorders. Biomolecules, 10(11).
Cassano, T., Villani, R., Pace, L., Carbone, A., Bukke, V. N., Orkisz, S., Avolio, C. & Serviddio, G. (2020). From Cannabis sativa to cannabidiol: Promising therapeutic candidate for the treatment of neurodegenerative diseases. Frontiers in Pharmacology, 11(2020).
Wiese, B., & Wilson-Poe, A. R. (2017). Emerging evidence for cannabis' role in opioid use disorder. Cannabis and Cannabinoid Research, 3(1), 179-189.
Hurd, Y. L., Spriggs, S., Alishayev, J., Winkel, G., Gurgov, K., Kudrich, C., Oprescu, A. M., & Salsitz, E. (2019). Cannabidiol for the reduction of cue-induced craving and anxiety in drug-abstinent individuals with heroin use disorder: A double-blind randomized placebo-controlled trial. The American Journal of Psychiatry, 176(11), 911–922.
Capano, A., Weaver, R., & Burkman, E. (2019). Evaluation of the effects of CBD hemp extract on opioid use and quality of life indicators in chronic pain patients: A prospective cohort study. Postgraduate Medicine, 132(1), 56-61.
Ayati, Z., Sarris, J., Chang, D., Emami, S. A., & Rahimi, R. (2020). Herbal medicines and phytochemicals for obsessive-compulsive disorder. Phytotherapy Research, 34(8), 1889-1901.
Murphy, R. A., Devarshi, P. P., Ekimura, S., Marshall, K., & Mitmesser, S. H. (2021). Long-chain omega-3 fatty acid serum concentrations across life stages in the USA: An analysis of NHANES 2011-2012. Nutrition and Metabolism, 11(5).
inhibitory component in cannabis.](https://pubmed.ncbi.nlm.nih.gov/18556441/) Drug Metabolism and Disposition: The Biological Fate of Chemicals. 36(9), 1917-1921.
Rock, E. M., Limebeer, C. L., Pertwee, R. G., Mechoulam, R., & Parker, L. A. (2021). Therapeutic potential of cannabidiol, cannabidiolic acid, and cannabidiolic acid methyl ester as treatments for nausea and vomiting. Cannabis and Cannabinoid Research, 6(4).