Best Vitamins for Energy

Find out which vitamins, minerals, and other supplements can help you maintain healthy energy levels.

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Last updated: Jan 8th, 2024
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Vitamins for Energy

Photo by Innerbody Research

Whether it’s a groggy morning or a mid-afternoon slump, just about everyone feels the need for an energy boost now and then. Many people reach for coffee or energy drinks to stay alert and awake throughout the day. But are there alternatives to these costly and generally unhealthy energy boosters?

Luckily, the answer is yes. Many vitamins, minerals, herbs, and other supplements can help boost energy by filling in nutrition gaps or helping your body produce more energy. Many of these products are all-natural and safe — and may be a better long-term solution for your fatigue than that daily espresso.

We found the best energy-boosting vitamins on the market, and this guide provides you with information about their price, ingredients, effectiveness, and more.

If you don’t have time to read the whole guide, check out our top six recommendations below.

Summary of recommendations

Our Top Choice

Tropical Oasis offers liquid multivitamins that are easy to take and absorb more thoroughly than pills.

Tropical Oasis Mega Plus contains 85 ingredients — vitamins, minerals, amino acids, and more — that can fill most potential gaps in the average diet. And its liquid form allows your body to absorb more of those vital nutrients.

Table of Contents

In this Review

Why you should trust us

At Innerbody Research, we extensively test each health service or product we review, including vitamin supplements for energy. Our testing team has ordered and taken these supplements themselves in order to provide you with honest, thorough reporting about the experience.

We’ve also spent hundreds of hours digesting scholarly journal articles regarding vitamins, minerals, amino acids, botanicals, and other ingredients commonly found in these supplements. Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles.

What are vitamins for energy?

When people talk about energy-boosting vitamins, they typically refer to a class of supplements that includes more than just vitamins. But this is true of most multivitamin supplements; despite the name, they contain more than just vitamins. Many include minerals, amino acids, healthy fats, enzymes, and botanical ingredients.

So, when we set out to look at the top energy-boosting vitamins on the market, we widened our search to include some products that have no actual vitamin content, but that are marketed and sold right alongside other multis.

If we were to limit ourselves to vitamins and vitamins alone, we’d have a poor set of recommendations for you. And the most important thing you could take from a guide like this one is a confident notion that a certain supplement can help you increase your energy levels in a safe, reliable way.

Supplements for energy: top considerations

When evaluating our top contenders, we kept four essential criteria in mind: effectiveness, safety, cost, and convenience. As you’ll see, different companies came out on top in specific criteria, but we gave more weight to things like effectiveness and cost, which ultimately led to our final rankings.

We also did something we rarely do in our evaluation criteria, which is to divide a criterion into two distinct categories. In this case, we looked at short-term effectiveness and long-term effectiveness separately.

We created this division because there are two distinct approaches to this supplement category. Some people will want a supplement they can take and immediately feel energized. Others will want something they can take daily to increase and stabilize energy levels gradually. These approaches require different ingredients, and we've decided to award winners for each.

Effectiveness: long-term

Winner: Tropical Oasis Mega Plus

Vitamin supplementation may not be as effective in those with healthy diets and a normally functioning metabolism. In cases where individuals get less than an ideal amount of one nutrient or another, supplements can fill the gap. If enough small deficiencies combine to create a drop in energy, a more comprehensive multivitamin supplement may be required to stabilize you. That’s why we looked for a supplement that offered a long list of well-considered ingredients to recommend for most people.

We’ve also spent a lot of time in this and other guides considering the topics of absorption and bioavailability as a way to help us determine the best products for your health. In the case of multivitamins, there is ample evidence that liquid solutions can outperform capsules or gummies in getting you the most out of your investment. So, between its long list of well-researched components and its liquid form, Tropical Oasis Mega Plus quickly emerged as the most effective long-term solution for increasing and maintaining energy levels.

Here’s a quick look at how Tropical Oasis outpaces its competitors in the sheer number of ingredients and competes with its closest competitors in terms of overall dose:

Total ingredient count (excluding delivery ones)Total dose from all ingredientsIngredient highlights
Tropical Oasis Mega Plus851,885mg1,200mg vitamin C, 80mcg vitamin B12, 198mg fulvic acid mineral water
Nootropics Depot Caffeine + L-Theanine2300mg100mg caffeine, 200mg L-theanine
Ritual Multi10370mg2,000IU vitamin D, 330mg omega-3s
Thesis Energy81,900mg300mg citicoline, 500mg n-acetyl cysteine, 100mg caffeine
Garden of Life Raw CoQ1027681mg200mg raw CoQ10, 444mg cold-pressed chia seed oil
LiveConscious B1215mg5mg vitamin B12
Olly Daily Energy3130mg300mcg vitamin B12, 100mg goji berry juice powder, 30mg CoQ10

Effectiveness: short-term

Winner: Nootropics Depot Caffeine + L-Theanine

Nootropics Depot offers a product that combines caffeine and L-theanine for enhanced focus and alertness without the negative side effects of caffeine alone. Many studies show that caffeine and L-theanine work well together. We’ve also seen evidence that a 2:1 ratio of L-theanine to caffeine bears superior effects than its inverse, especially with regard to jitteriness.

As a result, we found that Nootropics Depot’s combination of 100mg of caffeine and 200mg of L-theanine was an ideal dosage. It doesn’t provide much more caffeine than a large cup of coffee, either, so you could take it alongside your morning cup and not feel too wired.

Cost

Winner: Nootropics Depot Caffeine + L-Theanine

While it doesn't have the most ingredients of the supplements in this guide, and it has less potential for long-term energy maintenance, this caffeine and L-theanine combo is decidedly inexpensive. And if you decide you want to take a fair amount of it over the long haul, you can use Nootropics' Depot's bulk discount system to bring your cost per dose down to $0.16, less than half the next best option from LiveConscious.

That B12 supplements from LiveConscious and Olly's Daily Energy Gummy could be considered close runners-up here, though, especially when compared to others in the field. In fact, these three supplements are inexpensive enough that you could combine a fast-acting caffeine and L-theanine dose with a long-term dose of either LiveConscious B12 or Olly Daily Energy and still pay less than your pay for a single dose of Ritual's Multi or Thesis Energy.

Special Offer from Tropical Oasis: Save 25% when you subscribe.

Safety

Winner: Ritual

Generally speaking, the average multivitamin should be safe for most people, but there are certain medications that have contraindications with things as common as vitamin C. So, how do you choose a supplement for energy that’s safe? We like Ritual’s approach to this problem quite a bit. While Tropical Oasis’ 85 individual ingredients help ensure that you top up a large amount of vitamins and minerals, there are plenty of such nutrients you likely get from your diet in sufficient amounts.

With water-soluble nutrients, anything your body doesn’t need will just get eliminated in your urine. And the human body is really good at adjusting the way it metabolizes various nutrients based on its needs. Ritual’s approach is to fill more specialized gaps in the average diet based on research into what’s most likely to need a little boost. Things like calcium and vitamin C are absent from its multivitamin because the company is confident that most users get enough of these from food sources.

By intelligently selecting which nutrients to include and which to exclude, Ritual gives you a product that’s less likely to cause your kidneys or liver to have to do much extra work and less likely to present contraindications for certain medications or conditions. You might look at Ritual’s label and say that it still has ten ingredients; why isn’t something like OLLY’s Daily Energy Gummy or Nootropics Depot’s caffeine and L-theanine supplement even safer? They have just three and two active ingredients, respectively.

The reason we regard Ritual to be safer than the other competitors on this list is a little different when compared to each of them. For example, with OLLY or any gummy, dosing can be wildly inconsistent. And the risks of over-caffeination with Nootropics Depot’s product are significant for anyone who’d have a hard time simultaneously curtailing their daily coffee intake. Our testers found that adding the caffeine pills to their regimen without curtailing their coffee habits resulted in some discomfort, including jitteriness and headaches.

Convenience

Winner: OLLY

Adding a new daily vitamin to your routine must be simple. That way, you’re more likely to stay consistent with it and see long-term results. OLLY is our winner for convenience because it offers an energy gummy that you take just once daily with or without food and water. You don’t need to worry about pill size or keep anything in the refrigerator (though we have had gummies melt if left in hot environments like a car).

Garden of Life could be considered a strong runner-up in this category. The company’s CoQ10 supplement isn’t more convenient to take than OLLY’s gummies, but the company offers several gummies and liquids of its own, and it has the most generous money-back guarantee of the companies in this guide.

How our top recommendations compare

We’ve put a handy chart together comparing our top picks among vitamins for energy. You’ll see that the cost per day ranges from around $0.23 all the way up to $3.29, and we’ll get into the nuances that drive these prices in each products’ individual sections.

Tropical Oasis Mega Plus
Nootropics Depot Caffeine + L-Theanine
Ritual Multi
Thesis Energy
Garden of Life Raw CoQ10
LiveConscious B12
OLLY Daily Energy
Price for one order
$35
$14 or $28
$33
$119
$46
$25
$14 or $25
Number of servings
32
60 or 180
30
24
60
60
30 or 60
Cost per dose
$1.09
$0.23 or $0.16
$1.10
$3.29
$0.80
$0.42
$0.47
Delivery method
Liquid
Capsule
Capsule
Capsule
Capsule
Liquid
Gummy
Bulk or subscription deals available?
Subscription
Bulk
Program is subscription-only
Subscription
Subscription
Both
Both
Money-back guarantee (days)
None
30
30
30
60
30
30
Vegan?

What is energy in the first place?

You know what it’s like to feel energized, but what’s actually happening in your body to make you feel that way? Before you can understand how a supplement can boost your energy levels, it’s important to understand what energy is to begin with. It’s an immensely complicated system, but at its core, we can look at one compound responsible for most of your body’s energy: adenosine triphosphate (ATP).

ATP might only sound vaguely familiar to you if you slept through high school biology, but, an overabundance of its cousin adenosine is likely the reason you couldn’t stay awake in class. Here’s how it works in the simplest possible terms:

  1. You eat food.
  2. Your body breaks down that food into simple sugars.
  3. Those simple sugars break down further, eventually forming ATP.
  4. Your cells use ATP as a source of energy, leaving adenosine as a byproduct.
  5. Adenosine builds up in your body and connects to receptors that tell your brain to start getting tired.
  6. When enough adenosine builds up and connects to these receptors, you’ll fall asleep.
  7. Your body cycles the adenosine out of your system as you sleep.

You can think of your cells as the batteries that provide you with your energy and ATP as the chemical substance in the batteries that holds a charge. Sleeping or eating can recharge those batteries.

How caffeine fits into the adenosine cycle

Plain black coffee has very few calories and offers no sugars to the body unless you add them to the drink. So, how can it keep you awake and make you feel energized?

Caffeine and other xanthines, like theophylline in tea or theobromine in chocolate, block adenosine receptors. That means that as your body uses up ATP and builds up a storehouse of adenosine, it's not syncing up with your brain to tell you to get tired. But that adenosine is still there, and once the caffeine wears off, your body gets flooded with signals from its adenosine receptors, causing the dreaded crash. This is why even a short nap can be preferable to an afternoon cup of coffee; sleep is the most efficient way to clear adenosine from your system.

How vitamins and other supplements boost energy

There are many supplements you can take to boost energy levels. But it’s also important to note that most supplements don’t produce energy themselves. Energy comes from carbohydrates, fats, and proteins. However, some vitamins and minerals in dietary supplements can influence, support, or bolster body functions that do influence energy levels.

As we discussed above, supplements like caffeine can block adenosine receptors, preventing or reducing fatigue. Other supplements, like CoQ10, can increase ATP production or the efficiency of its utilization, providing you with a greater well of energy.

Which vitamins and other nutrients boost energy?

Some of the supplements in this guide have nearly 100 ingredients in them, many of which are there to improve your energy levels. To help you decide which approach best suits your needs, let’s look at how a few mainstays in these products actually work:

Vitamin B12 and other B vitamins

You can find B12 in dietary staples like meat, fish, and dairy products, but as we age, our bodies are less adept at processing B12. This vitamin is important for helping your body convert food into energy. Vegans and vegetarians are at risk for B12 deficiencies, so ensuring supplementation is critical. Other B vitamins play similar roles, though specific forms of B3, such as nicotinamide riboside, have even tighter links to ATP and cellular health than others.

Vitamin D

Vitamin D is critical for numerous bodily functions, including energy metabolism. It’s one of the few vitamins for which many Americans are at risk for deficiency, with recent statistics showing a 2.6% prevalence of severe deficiency and a 22% prevalence of moderate deficiency. In men, vitamin D is closely tied to testosterone, which is vital for energy production and other processes.

Iron

Your body uses iron to produce hemoglobin, which transports oxygen to your body’s tissues. An iron deficiency is known as anemia, which can cause fatigue, among other complications.

CoQ10

Coenzyme Q10 is found in every cell in the body and helps make energy, so when levels of CoQ10 drop, so do energy levels. Supplementing with CoQ10 reduces fatigue.

Caffeine with L-theanine

Most people are aware of caffeine’s energy-boosting effects but may also know of its side effects, like a racing heart, anxiety, and irritability. L-Theanine is an amino acid that, when used in combination with caffeine, reduces those unwanted side effects. The balance between the two is important for achieving this effect, with a relative 2:1 ratio of L-theanine to caffeine showing the most promise in studies.

Magnesium

Magnesium helps the body metabolize glucose and turn it into energy. Without enough magnesium, you can feel fatigued or even experience muscle weakness, depression, or high blood pressure.

Polyols and amino acids

Certain sugar alcohols and amino acids play a role in increasing the bioavailability of specific vitamins and minerals. This is why you see inositol and a large amino acid complex in Tropical Oasis’ liquid multivitamins. Its amino acid complex appears in far too small a dose to be impactful the way true amino acid supplementation would be, but it serves to enhance the product’s other ingredients.

Omega-3 fatty acids

Omega-3 fatty acids offer several important health benefits, but their influence on mitochondrial function (where ATP is produced) is well-documented in several studies.

Citicoline

Citicoline appears to play a role in producing energy for the brain. It also converts to phosphatidylcholine, a phospholipid involved in energy production throughout the body.

Are energy-boosting supplements a good choice for you?

Vitamins that boost energy are a good choice if you don’t get enough nutrients in your diet to yield high energy levels. If you have a vitamin deficiency or are malnourished, taking dietary supplements may be a good choice for you in general, not just to bolster your energy.

For example, if you have a nutrient deficiency because you follow a restrictive diet, you may have low energy levels that could benefit from energy-boosting vitamins. While getting the daily recommended nutrients from your diet is ideal, this is not always possible for all, so supplementation is necessary.

You may also benefit from energy-boosting vitamins if you live with digestive issues that don’t allow your body to absorb enough nutrients from food. If you have a condition like Crohn’s disease or colitis, you may notice low energy levels that could be improved by taking a daily vitamin.

If you are currently cutting calories to lose weight or following a new diet plan, you may also notice that your energy levels have taken a nosedive. Keeping track of what you eat and what vitamins and minerals you may be lacking can help you decide which type of energy-boosting supplement may be best for you.

Who should avoid them

You should avoid an energy-boosting supplement if you already get the daily recommended amount of that vitamin or mineral in your daily diet. Some common ingredients in these products can cause side effects if over-consumed. In capsule form, many vitamin supplements have been known to cause nausea.

Some energy-boosting vitamins include caffeine, so avoiding these products is important if you have caffeine sensitivity. In addition, some components may interfere with the efficacy of certain prescription medications. Consult your doctor before beginning any new vitamin or supplement to ensure it’s safe for you to consume.

Are energy-boosting supplements safe?

Generally, most energy-boosting supplements are safe for healthy adults when taken as directed. Most of these products are made with common ingredients and include low doses of vitamins and minerals that should gently supplement your diet.

However, some supplements include ingredients that could cause severe side effects if not taken in moderation. For example, taking too much iron can lead to digestive issues like nausea or vomiting and may even lead to more severe consequences like organ damage or internal bleeding. Make sure you’re taking only the amount necessary of each ingredient to avoid these issues and consult your doctor before beginning any new supplement.

Over-consuming caffeine — a common ingredient in some energy boosters — can also lead to negative consequences like headaches, quick heart rate, or dehydration. If you live with a chronic condition, take daily prescription or over-the-counter medication, or are nursing or pregnant, it’s a good idea to avoid energy-boosting vitamins until you speak with a healthcare provider.

Tropical Oasis Mega Plus

Best for most people and best liquid vitamin

Tropical Oasis Mega Plus

Photo by Innerbody Research

Pros

  • Liquid delivery should absorb faster and more thoroughly
  • Initial taste is citrusy and pleasant
  • Contains 85 supplemental ingredients
  • Mineral content comes mostly from fulvic acid water
  • Deep 25% discount for subscribers

Cons

  • Aftertaste is a bit bitter
  • No measurement markings inside of cap (you’ll need another way to measure)
  • Has to be kept in the refrigerator
  • Not suitable for vegans or vegetarians
  • May not be suitable for those with FODMAP sensitivities
  • No returns accepted

A comprehensive multivitamin is a good place to start if you’re experiencing a lack of energy, and you don’t want to spend time testing individual vitamins or minerals to see if you can identify a minor deficiency. There’s a good chance that one or two of the 85 ingredients in Tropical Oasis Mega Plus will fill a gap that may be present in your diet.

The individual doses of each ingredient aren’t outlandish either. In some vitamin supplements, you’ll get thousands of times your daily requirement in a single dose — so-called megadosing — which proponents believe can circumvent any absorption or bioavailability issues. But by using a liquid delivery system, Tropical Oasis doesn’t need to megadose to get you appropriate amounts of its ingredients.

Here’s a look at the ingredients on the label:

Tropical Oasis Mega Plus Ingredients

Photo by Innerbody Research

Of course, one question reigns supreme when we’re talking about liquid vitamin supplements: How do they taste?

In Tropical Oasis’ case, the taste is fine. Our testers didn’t love it, but it wasn’t bad enough that they couldn’t drink a small amount daily. One tester described it as like drinking half a glass of Sunny Delight or a similar, cheaply made orange juice, then eating a few children’s chewable vitamins. And that sums it up nicely. The initial taste is citrusy without being too sweet. In fact, it’s rather acidic. That acidity gives way to a fruity bitterness reminiscent of Flintstones' chewable vitamins.

Compared to something like OLLY’s gummy vitamins, the taste is inferior. Those gummies have a little bitterness of their own, but they are noticeably sweeter, as well.

Each bottle contains 32 doses rather than 30. This ensures that you won't run out on months that contain 31 days, but it also guards against any spillage. This is a necessary measure when considering that the inside of the cap isn't labeled with any dosing lines.

We would have liked it if that cap had a line for the 2-tbsp (30mL) dose, which would allow you to measure without added implements (not everyone has miniature graduated beakers like we do).

Tropical Oasis pricing, shipping, and returns

A bottle of Tropical Oasis Mega Plus costs $34.95, but a 25% discount for subscribers brings that cost down to $24.71. The company offers free shipping on orders over $60, which is a higher threshold than a company like Garden of Life has, but it’s roughly in line with thresholds from OLLY and Nootropics Depot.

Tropical Oasis is the only company in our guide that doesn’t offer returns on any of its products.

Nootropics Depot Caffeine + L-Theanine Capsules

Best budget pick

Nootropics Depot Caffeine I Theanine

Photo by Innerbody Research

Pros

  • L-Theanine balances out caffeine side effects
  • Uses in-house and third-party lab testing
  • Customizable formula (to a degree)
  • Can be taken in conjunction with most other supplements in this guide
  • 30-day return policy
  • Free shipping on orders over $50

Cons

  • May produce a crash in some users
  • No subscription options
  • Return policy only covers unused products

Almost everyone knows the energy-boosting benefits of caffeine, but many people also experience its drawbacks: irritability, anxiety, jitteriness, insomnia, and the inevitable energy crash. Products like Nootropics Depot’s Caffeine + L-Theanine Capsules combine caffeine with the amino acid L-theanine, another energy booster that counteracts caffeine's side effects. These two ingredients work in synergy to improve your focus and alertness without making you feel restless or jumpy. That said, it’s still possible for you to experience a crash depending on your diet and sleep habits surrounding its use.

The company tests its products in an in-house laboratory and partners with seven third-party labs to double-check the quality and purity of all supplements. In addition, you can choose which combination of caffeine and L-theanine works best for you when making a purchase. Choose from:

  • Caffeine (100mg) + L-theanine (200mg)
  • Caffeine (200mg) + L-theanine (100mg)

This is helpful for people who are sensitive to caffeine and would benefit from a lower dose, and it also helps people who need an extra boost of caffeine for energy production. That said, studies have shown that the synergistic effect between the two substances is more pronounced at a 2:1 L-theanine to caffeine ratio.

The company warns that the product contains pure caffeine, and abusing it can cause severe side effects. Make sure to take the supplement as directed, which is one capsule once or twice a day.

Nootropics Depot price, shipping, and returns

Nootropics Depot offers free shipping on domestic orders over $50 and international orders over $200.

You can choose from a 60-count or 180-count bottle of capsules, and prices vary depending on the caffeine and L-theanine levels. Here is the price breakdown.

  • 100mg Caffeine + 200mg L-theanine (60 count): $13.99
  • 100mg Caffeine + 200mg L-theanine (180 count): $27.99
  • 200mg Caffeine + 100mg L-theanine (60 count): $14.99
  • 200mg Caffeine + 100mg L-theanine (180 count): $29.99

A 30-day return policy covers unopened products, but the company does not provide refunds for opened or used vitamins. Other companies, like Ritual, offer the same time frame but allow you to try the product first and still return it if you aren’t satisfied.

Ritual Multivitamins

Best capsule

Ritual Mens Multi

Photo by Innerbody Research

Pros

  • Multivitamins contain several energy-boosting ingredients
  • Vegan-friendly
  • Third-party tested
  • Transparent about ingredients, suppliers, and effectiveness
  • Company subjects its supplements to rigorous clinical studies
  • Includes B12, iron, magnesium, and omega-3s
  • 30-day money-back guarantee
  • Free shipping

Cons

  • Auto-enrollment in a monthly subscription
  • Omega-3 microalgae source can cause an aftertaste
  • Our testers had occasional shipping issues

We chose Ritual Multivitamins as the best capsule because the company takes a considered approach to what it includes in its supplement and encapsulates those ingredients in a delayed-release capsule that increases their absorption potential. In addition, the company is committed to using traceable ingredients in all of its products, meaning Ritual provides the source and suppliers of each ingredient and any clinical studies showing their efficacy. These vegan multivitamins are also third-party tested for safety and quality and don’t contain GMOs or artificial colors.

As an example of energy-boosting ingredients, we’ll take a closer look at Ritual’s Essential for Women Multivitamin 18+. In addition to several other ingredients, this vitamin includes some components known for energy production, including:

  • Vitamin B12: 8mcg
  • Iron: 8mg
  • Magnesium: 30mg
  • Omega-3: 330mg

In a clinical trial, Ritual’s multivitamin for women significantly increased vitamin D and omega-3 levels in 94 adult women over 12 weeks.

Ritual also provides a wide array of other products. Here is a list of its other multivitamin options:

  • Essential for Women Multivitamin 50+
  • Essential for Women Prenatal Multivitamin
  • Essential for Women Postnatal Multivitamin
  • Essential for Men Multivitamin 18+
  • Essential for Men Multivitamin 50+
  • Essential for Teens Multivitamin for Her
  • Essential for Teens Multivitamin for Him
  • Essential for Kids Multivitamin 4+

Ritual pricing, shipping, and returns

All of Ritual’s multivitamin products cost between $30-$35. When you purchase a Ritual product, you are automatically enrolled in a subscription service that auto-delivers every 30 days. It includes free shipping and the ability to set your delivery date and pause or delay shipments as needed.

In testing, one of our testers had an issue with delivery, as their packages were being marked return to sender without any delivery attempt. This would cause the package to bounce around the area between the shipping center and our tester’s address until they contacted the company to investigate. The problem recurred on three successive shipments.

This could very well have been a postal service issue and not a Ritual issue, but it’s troubling that no one on Ritual’s side ever reached out when a package went more than two weeks past its shipment date without having been delivered. When we did reach out to Ritual, they quickly overnighted replacements that arrived without a problem.

Your order is covered by a 30-day money-back guarantee, which Ritual considers a trial period. If you don’t enjoy the product during that time, return it for a refund and cancel your subscription with no questions asked. This is a little more generous than 30-day policies from companies like Nootropics Depot, which only accepts returns on unopened products.

Thesis Energy

Best nootropic for energy

Thesis Energy

Photo by Innerbody Research

Pros

  • Ingredients have strong research behind them
  • Available with or without caffeine
  • Subscriptions include free nootropic coaching
  • Great customer support
  • 30-day money-back guarantee

Cons

  • Most expensive option in our guide
  • Only 24 doses per shipment
  • Some of our testers experienced crashes from the caffeinated formula

Thesis is one of the most prominent nootropics companies out there, with products we regard as among the most effective available. It combines a limited number of ingredients per blend and offers six blends curated for specific needs. Those blends include:

  • Energy
  • Motivation
  • Clarity
  • Logic
  • Creativity
  • Confidence

Thesis Energy contains some ingredients you don’t see in any other product in our guide. Here’s the full list:

  • Citicoline: 300mg
  • Mango Leaf: 300mg
  • Theacrine: 100mg
  • N-Acetyl Cysteine: 500mg
  • Indian Trumpet Tree: 100mg
  • N-Acetyl L-Tyrosine: 300mg
  • Caffeine: 100mg
  • L-Theanine: 200mg

Among ingredients unique to Thesis in our guide, mango leaf appears as a provider of several minerals associated with energy metabolism. And Theacrine (a branded substance similar to caffeine) has been shown in studies to elevate both energy levels and mood. Citicoline is similar to the choline found in Tropical Oasis products, but research indicates it may be the superior choice in both efficacy and safety.

If you’re new to the world of nootropics, you can make good use of the free coaching Thesis provides to all of its subscribers. Our testers have a long history with nootropics, both in trying several dozen different brands and in closely following the latest research. So, when we reached out to Thesis coaches, we thought we might challenge their knowledge base a bit. To our delight, they kept up with us on even the most nuanced of nootropic topics. But this led us to suspect that they might not be able to simplify complex nootropic science for average customers. So, we called back up and pretended to know nothing about the drug class. Again, to our delight, the coaches kept things simple but informative.

You can choose to exclude the caffeine and L-theanine from your shipment, but that won’t lower the cost of the products. And our testing has revealed that the caffeine and L-theanine are confined to one of three capsules in each individually packed dose. That means you can order the product with the caffeine and L-theanine and choose whether or not to take that capsule as part of any given dose.

Here's a look at the three capsules in a typical caffeinated dose of Thesis Energy. The one capsule that's off-white (compared to the two capsules containing a brownish mixture) is the caffeine and L-theanine capsule:

Thesis Energy Caffeine Pill Closeup

Photo by Innerbody Research

In testing, some members of our team found it necessary to remove the caffeine capsule from the blend, as they experienced heavy crashes after a period of sustained and active focus. But others were able to enjoy the full blend without side effects or crashes. This is why we recommend getting it with caffeine and testing each version to see what treats you better.

Thesis Energy pricing, shipping, and returns

Thesis pricing is where things get difficult for a lot of potential customers. The company ships you four small boxes once each month, and each small box contains any one of the company's six formulas in six individually packed doses. That’s 24 doses/month. And that box costs $119 as a one-time purchase or $79/month as a subscription.

Shipping is free, and the company’s 30-day return policy lets you try up to four blends before deciding if it’s right for you.

Garden of Life Raw CoQ10

Best CoQ10 supplement

Garden of Life Raw CoQ10 Pills

Photo by Innerbody Research

Pros

  • Contains pure, raw ingredients
  • Includes CoQ10, probiotics, chia seed oil, fruits, and veggies
  • No artificial ingredients
  • Free from dairy, GMOs, and gluten
  • Certified vegan and kosher
  • 60-day money-back guarantee

Cons

  • Contains soy
  • A bit on the pricey side
  • CoQ10 has several contraindications to consider

Each capsule of Garden of Life’s Raw CoQ10 vitamin contains cold-pressed chia seed oil, raw CoQ10, probiotics, and a fruit and vegetable complex that delivers antioxidants, omega-3s, and other nutrients for various health benefits. The term “raw” in this instance means that the vitamin doesn’t include any synthetic ingredients like sweeteners, fillers, colors, or additives. And we selected this as the best CoQ10 supplement because it delivers ingredients that can help with energy production and:

  • Cardiovascular function
  • Heart health
  • Antioxidant support
  • Cellular growth
  • Healthy aging

The supplement does not contain GMOs, dairy, or gluten and is certified vegan and kosher.

Garden of Life pricing, shipping, and returns

Garden of Life is a bit pricier than most other vitamins in this guide, with one jar of capsules costing $47.99 (up from $45.59 when we last reviewed it). But each jar includes 60 capsules, which is a two-month supply. Your purchase on the Garden of Life site is covered by a 30-day return policy, and the company offers free shipping on purchases over $25. Orders under $25 pay standard ground shipping fees.

The company used to avoid offering subscription discounts, but it’s recently integrated them for many of its products, including its Raw CoQ10. Subscribers can save 15%, bringing the cost down to $40.79 per bottle.

LiveConscious Vegan B12

Best B12 supplement

Liveconscious B12

Photo by Innerbody Research

Pros

  • Contains a megadose of B12
  • Tastes very pleasant
  • Bulk and subscription discounts available
  • Free shipping for subscribers

Cons

  • Likely much more B12 than you need
  • May stain if spilled
  • Convoluted return policy

LiveConscious B12 is the simplest product in our guide. Vitamin B12 deficiency has been shown to impair energy metabolism, though its administration as an intravenous injection for fatigue and weight loss has long been deemed ineffective.

A study from 2009 found that around 6% of people in the U.S. and UK were deficient in B12. But these numbers climb rapidly among vegans and vegetarians who see deficiency numbers nearly double that.

The National Institutes of Health recommends up to 2.8mcg of B12 daily, but LiveConscious provides you with 5,000mcg per dose. B12 is a water-soluble vitamin, so even though LiveConscious’ megadose is likely a heck of a lot more than your body needs, any excess will be filtered out and removed with your urine. If you’re worried about wasting all that B12, you could always take a smaller amount of the dropper with each dose, both reducing wasted B12 and stretching out your investment.

LiveConscious B12 pricing, shipping, and returns

LiveConscious offers both bulk and subscription discount opportunities to its customers. Here’s how its pricing works out:

One bottleTwo bottlesFour bottles
One-time purchase price$24.95$47.40$89.76
One-time purchase cost per bottle$24.95$23.70$22.44
Subscription price$22.45$42.40$79.84
Subscription cost per bottle$22.45$21.20$19.96

LiveConscious offers free shipping for subscribers and orders over $50. Smaller one-time orders incur a $5.95 shipping charge.

The company’s money-back guarantee is a little confusing. There’s a heavy emphasis on a 365-day money-back guarantee, which makes it sound like you could try the product for up to a year and get your money back if you don't like it. This isn’t the case. In reality, you have a year to initiate a return on any unopened products or up to two opened products. For subscribers, this only applies to your most recent order. And there’s a 15% restocking fee for unopened returns, as well.

Ultimately, there are some situations in which this could benefit someone who wanted to try a product for a while and wouldn’t mind only getting some of their investment back if it didn’t work out. But those cases will likely be far less frequent than ones in which people are taken by surprise by the nuances of the guarantee.

OLLY Daily Energy Gummy

Best gummy

Pros

  • Combines B12, CoQ10, and goji berry
  • Tasty tropical passion flavor
  • NSF-certified and gluten-free
  • One of the least expensive options in our guide
  • 30-day money-back guarantee

Cons

  • Contains gelatin
  • Subscription program can be confusing
  • Free shipping threshold is far from product’s price
  • Gummies notoriously have inaccurate doses

OLLY Daily Energy Gummy is our top pick for best gummy because it includes two of the most well-known energy-boosting ingredients: vitamin B12 (300mcg) and CoQ10 (30mg). Whether the addition of goji berry makes a meaningful difference for energy production is unclear; there’s too little sound science to support these claims and some studies that contradict them.

Our testers found the gummies to be tasty. The tropical flavor blended nicely with the hint of flavor coming from the active ingredients. These would not be difficult to take on a regular basis.

Like many gummy products, the energy supplement from OLLY contains gelatin and may not hold up in hot conditions. We’ve had similar gummies melt on us from exposure to temperatures above 80 degrees Fahrenheit, though we haven’t seen that with OLLY gummies specifically.

Perhaps the most worrying thing about gummies, in general, is that they tend to contain doses that disagree with whatever’s on the label. A prominent study of melatonin gummies illustrates this. Essentially, the rate of degradation in a gummy is high enough that they often leave their production facilities at higher doses than those listed on the label with the expectation that they’ll reach roughly that dose by the time they end up in a consumer’s hands. But there are so many variables in this equation that it’s next to impossible to know how much of any given ingredient you’re getting with gummies.

Still, higher doses of OLLY’s main ingredients here shouldn’t pose too much of a danger, and lower doses only stand to disappoint, not put you in harm’s way. If you prefer gummies for their taste and convenience, these are among the best you can get for energy supplementation.

OLLY pricing, shipping, and returns

OLLY offers free shipping on orders over $59 and a flat rate of $6.99 for shipping orders under that. The company also provides a 30-day money-back guarantee.

OLLY’s Daily Energy Gummies are available in bottles of 30 gummies or pouches of 60 with the option to subscribe for added savings. Here’s how that works out:

30-serving bottle60-serving pouch
One-time purchase price$13.99$24.99
One-time purchase cost per dose$0.47$0.42
Subscription price$11.89$21.24
Subscription cost per dose$0.40$0.35

Shipping is free on OLLY orders above $59, which is fine, but when you look at the average cost of the company’s supplements, you’ll see you’d have to buy several to reach this threshold.

If you’re unhappy with an OLLY purchase, you can return it for up to 30 days. This isn't an especially long time, but it does cover opened products, giving you a chance to try them and still get your money back, which isn’t offered by companies like Tropical Oasis or Nootropics Depot.

Frequently asked questions

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Sources

Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

  1. National Institutes of Health. (2018). Energy Drinks. National Center for Complementary and Integrative Health. NIH.

  2. Beal, T., White, J. M., Arsenault, J. E., Okronipa, H., Hinnouho, G., & Morris, S. S. (2021). Comprehensive Nutrient Gap Assessment (CONGA): A method for identifying the public health significance of nutrient gaps. Nutrition Reviews, 79(Supplement 1), 4-15.

  3. Johns Hopkins Medicine. (n.d.). Is There Really Any Benefit to Multivitamins? Johns Hopkins.

  4. Schrauzer, G.N. (1998). An Evaluation of Liquid Vitamin-Mineral Supplement Technology. Journal of Medicinal Food 1:3, 207-216

  5. Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., & Scholey, A. B. (2008). The effects of l-theanine, caffeine and their combination on cognition and mood. Biological Psychology, 77(2), 113-122.

  6. Kelly, S. P., Gomez-Ramirez, M., Montesi, J. L., & Foxe, J. J. (2008). L-Theanine and Caffeine in Combination Affect Human Cognition as Evidenced by Oscillatory alpha-Band Activity and Attention Task Performance. The Journal of Nutrition, 138(8), 1572S-1577S.

  7. Abdullah, M., Jamil, R.T., Attia, F.N. (2023). Vitamin C (Ascorbic Acid). StatPearls Publishing.

  8. National Research Council (US) Committee on Diet and Health. Diet and Health: Implications for Reducing Chronic Disease Risk. (1989). Water-Soluble Vitamins. Washington (DC): National Academies Press (US);. 12

  9. Dunn, J., Grider, M.H. (2023). Physiology, Adenosine Triphosphate. StatPearls Publishing.

  10. Meurer, F., Do, H. T., Sadowski, G., & Held, C. (2017). Standard Gibbs energy of metabolic reactions: II. Glucose-6-phosphatase reaction and ATP hydrolysis. Biophysical Chemistry, 223, 30–38.

  11. Daly, J. W., Shi, D., Nikodijevic, O., & Jacobson, K. A. (1994). The role of adenosine receptors in the central action of caffeine. Pharmacopsychoecologia, 7(2), 201.

  12. Lam, Y. Y., & Ravussin, E. (2016). Analysis of energy metabolism in humans: A review of methodologies. Molecular Metabolism, 5(11), 1057-1071.

  13. National Institutes of Health. (2021). Vitamin B12 Fact Sheet for Consumers. Office of Dietary Supplements.

  14. Samman, S. (2010). Vitamin B12 in Health and Disease. Nutrients, 2(3), 299-316.

  15. Hunt, A., Harrington, D., Robinson, S.(2014). Vitamin B12 deficiency. BMJ 2014; 349 :g5226

  16. Kennedy, D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review. Nutrients, 8(2), 68.

  17. Conze, D., Brenner, C., & Kruger, C. L. (2019). Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults. Scientific Reports, 9.

  18. Carlberg, C. (2022). Vitamin D in the Context of Evolution. Nutrients, 14(15), 3018.

  19. Cui, A., Xiao, P., Ma, Y., Fan, Z., Zhou, F., Zheng, J., & Zhang, L. (2022). Prevalence, trend, and predictor analyses of vitamin D deficiency in the US population, 2001–2018. Frontiers in Nutrition, 9, 965376.

  20. Monson, N. R., Klair, N., Patel, U., Saxena, A., Patel, D., Ayesha, I. E., & Nath, T. S. (2023). Association Between Vitamin D Deficiency and Testosterone Levels in Adult Males: A Systematic Review. Cureus, 15(9).

  21. Medline Plus. (2015). Iron. National Institutes of Health, National Library of Medicine.

  22. National Institutes of Health. (2022). Anemia: What is Anemia? National Heart, Lung, and Blood Institute.

  23. Medline Plus. (2017). Primary coenzyme Q10 deficiency. National Institutes of Health, National Library of Medicine.

  24. Mehrabani, S., Askari, G., Miraghajani, M., Tavakoly, R., & Arab, A. (2019). Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies. Complementary Therapies in Medicine, 43, 181–187.

  25. Medline Plus. (2021). Caffeine. National Institutes of Health, National Library of Medicine.

  26. Giesbrecht, T., Rycroft, J. A., Rowson, M. J., & De Bruin, E. A. (2010). The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness. Nutritional Neuroscience, 13(6), 283–290.

  27. Al Alawi, A. M., Majoni, S. W., & Falhammar, H. (2018). Magnesium and Human Health: Perspectives and Research Directions. International Journal of Endocrinology, 2018.

  28. Zhang, X., Li, Y., Del Gobbo, L. C., Rosanoff, A., Wang, J., Zhang, W., & Song, Y. (2016). Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials. Hypertension (Dallas, Tex. : 1979), 68(2), 324–333.

  29. Melse-Boonstra, A. (2020). Bioavailability of Micronutrients From Nutrient-Dense Whole Foods: Zooming in on Dairy, Vegetables, and Fruits. Frontiers in Nutrition, 7.

  30. De Oliveira, M. R., Nabavi, S. F., Nabavi, S. M., & Jardim, F. R. (2017). Omega-3 polyunsaturated fatty acids and mitochondria, back to the future. Trends in Food Science & Technology, 67, 76-92.

  31. Silveri, M. M., Dikan, J., Ross, A. J., Jensen, J. E., Kamiya, T., Kawada, Y., Renshaw, P. F., & Yurgelun-Todd, D. A. (2008). Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy. NMR in Biomedicine, 21(10), 1066-1075.

  32. Van der Veen, J. N., Kennelly, J. P., Wan, S., Vance, J. E., Vance, D. E., & Jacobs, R. L. (2017). The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1859(9), 1558-1572.

  33. Nocerino, A., Nguyen, A., Agrawal, M., Mone, A., Lakhani, K., & Swaminath, A. (2020). Fatigue in Inflammatory Bowel Diseases: Etiologies and Management. Advances in Therapy, 37(1), 97-112.

  34. Bo, S., Fadda, M., Fedele, D., Pellegrini, M., Ghigo, E., & Pellegrini, N. (2020). A Critical Review on the Role of Food and Nutrition in the Energy Balance. Nutrients, 12(4).

  35. Yuen, H.W., Becker, W. (2023). Iron Toxicity. StatPearls Publishing.

  36. Murray, A., Traylor, J. (2023). Caffeine Toxicity. StatPearls Publishing.

  37. Sohail, A. A., Ortiz, F., Varghese, T., Fabara, S. P., Batth, A. S., Sandesara, D. P., Sabir, A., Khurana, M., Datta, S., & Patel, U. K. (2021). The Cognitive-Enhancing Outcomes of Caffeine and L-theanine: A Systematic Review. Cureus, 13(12).

  38. Osburn, S. C., Roberson, P. A., Medler, J. A., Shake, J., Arnold, R. D., Alamdari, N., Bucci, L. R., Vance, A., Sharafi, M., Young, K. C., & Roberts, M. D. (2021). Effects of 12-Week Multivitamin and Omega-3 Supplementation on Micronutrient Levels and Red Blood Cell Fatty Acids in Pre-menopausal Women. Frontiers in Nutrition, 8.

  39. Kumar, M., Saurabh, V., Tomar, M., Hasan, M., Changan, S., Sasi, M., Maheshwari, C., Prajapati, U., Singh, S., Prajapat, R. K., Dhumal, S., Punia, S., Amarowicz, R., & Mekhemar, M. (2021). Mango (Mangifera indica L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities. Antioxidants, 10(2).

  40. Kuhman, D. J., Joyner, K. J., & Bloomer, R. J. (2015). Cognitive Performance and Mood Following Ingestion of a Theacrine-Containing Dietary Supplement, Caffeine, or Placebo by Young Men and Women. Nutrients, 7(11), 9618-9632.

  41. Synoradzki, K., & Grieb, P. (2019). Citicoline: A Superior Form of Choline? Nutrients, 11(7).

  42. Medline Plus. (2022). Healthy food trends -- chia seeds. National Institutes of Health, National Library of Medicine.

  43. Hernández-Camacho, J. D., Bernier, M., López-Lluch, G., & Navas, P. (2018). Coenzyme Q10 Supplementation in Aging and Disease. Frontiers in Physiology, 9.

  44. Guéant, J., Caillerez-Fofou, M., Battaglia-Hsu, S., Alberto, J., Freund, J., Dulluc, I., Adjalla, C., Maury, F., Merle, C., Nicolas, J., Namour, F., & Daval, J. (2013). Molecular and cellular effects of vitamin B12 in brain, myocardium and liver through its role as co-factor of methionine synthase. Biochimie, 95(5), 1033-1040.

  45. Mayo Clinic. (2022). Are vitamin B-12 injections helpful for weight loss? Mayo Foundation for Medical Education and Research (MFMER).

  46. Vidović, B. B., Milinčić, D. D., Marčetić, M. D., Djuriš, J. D., Ilić, T. D., Kostić, A. Ž., & Pešić, M. B. (2022). Health Benefits and Applications of Goji Berries in Functional Food Products Development: A Review. Antioxidants, 11(2).

  47. Cohen, P. A., Avula, B., Wang, H., Katragunta, K., & Khan, I. (2023). Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US. JAMA, 329(16), 1401-1402.

  48. Popkin, B. M., & Rosenberg, I. H. (2010). Water, Hydration and Health. Nutrition Reviews, 68(8), 439.

  49. Holst, S.C., Landolt, HP. (2015). Sleep Homeostasis, Metabolism, and Adenosine. Curr Sleep Medicine Rep 1, 27–37.

  50. A. Wender, C. L., & Manninen, M. (2022). The Effect of Chronic Exercise on Energy and Fatigue States: A Systematic Review and Meta-Analysis of Randomized Trials. Frontiers in Psychology, 13.

  51. Tardy, L., Pouteau, E., Marquez, D., Yilmaz, C., & Scholey, A. (2020). Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Nutrients, 12(1).

  52. Abdulhasan, M. K., Li, Q., Dai, J., Abu-Soud, H. M., Puscheck, E. E., & Rappolee, D. A. (2017). CoQ10 increases mitochondrial mass and polarization, ATP and Oct4 potency levels, and bovine oocyte MII during IVM while decreasing AMPK activity and oocyte death. Journal of Assisted Reproduction and Genetics, 34(12), 1595-1607.